Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 8/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | MTOR | P42345 | 5/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | JAK2 | O60674 | 1/20 | 0.37 |
| ▸ | JAK3 | P52333 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1646777 | 0.83 | MAPT (0.62) | DGAT1MAPTALDH1A1HTTLMNA | |
| SCHEMBL943584 | 0.82 | PANK3 (0.41) | DGAT1MAPTALDH1A1HTTLMNA | |
| SCHEMBL943790 | 0.81 | THRB (0.44) | MAPTALDH1A1HTTLMNAGAA | |
| SCHEMBL944196 | 0.81 | CNR1 (0.40) | MAPTALDH1A1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL942282 | 0.81 | USP2 (0.41) | MAPTALDH1A1POLBGAAHSD17B10 | |
| SCHEMBL943643 | 0.81 | WNT3A (0.40) | DGAT1MAPTHTTLMNASMN1; SMN2 | |
| SCHEMBL944509 | 0.80 | MAPT (0.39) | MAPTALDH1A1HTTLMNAGAA | |
| SCHEMBL942621 | 0.80 | MAPT (0.44) | MAPTALDH1A1HTTLMNAGAA | |
| SCHEMBL944261 | 0.80 | SMN1; SMN2 (0.44) | MAPTALDH1A1HTTSMN1; SMN2RAB9A | |
| SCHEMBL942180 | 0.80 | CNR1 (0.41) | MAPTALDH1A1POLBGAASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2173749-B1 | 2-OXO-2- (2-PHENYL-5,6,7,8-TETRAHYDRO-INDOLIZIN-3-YL) -ACETAMIDE DERIVATIVES AND RELATED COMPOUNDS AS ANTIFUNGAL AGENTS | F2G LTD (GB) | 2011-01-12 | — | — | EP | claimed |