Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS1R3 | Q7RTX0 | 3/20 | 0.32 |
| ▸ | TAS1R1 | Q7RTX1 | 3/20 | 0.32 |
| ▸ | TAS1R2 | Q8TE23 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10199845 | 0.93 | NR1I2 (0.31) | ALDH1A1HPGDMAPK1MAOAGAA | |
| SCHEMBL8713502 | 0.89 | TAS1R3 (0.36) | TAS1R3TAS1R1TAS1R2HPGDGAA | |
| SCHEMBL9883891 | 0.88 | HTR2A (0.36) | MAOA | |
| SCHEMBL812223 | 0.87 | CYP1A2 (0.32) | HPGDSMN1; SMN2 | |
| SCHEMBL10309318 | 0.86 | PTGDR2 (0.31) | — | |
| SCHEMBL8015573 | 0.86 | TAS1R3 (0.33) | TAS1R3TAS1R1TAS1R2HPGDGAA | |
| SCHEMBL10199695 | 0.82 | CCR1 (0.32) | SMN1; SMN2 | |
| SCHEMBL812144 | 0.81 | ACACB (0.33) | MAPK1 | |
| SCHEMBL10199736 | 0.78 | PDE4A (0.32) | ALDH1A1HSD17B10HPGDMAPK1ATM | |
| SCHEMBL10199912 | 0.78 | PPOX (0.31) | ALDH1A1HSD17B10HPGDMAPK1ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120238450-A1 | C2-PHENYL-SUBSTITUTED CYCLIC KETONOLS | BAYER AKTIENGESELLSCHAFT (DE) | 2012-09-20 | — | — | US | disclosed |
| US-8168832-B2 | 2,4,6-trialkylphenyl substituted cyclopentane-1,3-dione | BAYER CROPSCIENCE AG (DE) | 2012-05-01 | — | — | US | disclosed |
| US-8168832-B2 | 2,4,6-trialkylphenyl substituted cyclopentane-1,3-dione | BAYER CROPSCIENCE AG (DE) | 2012-05-01 | — | — | US | disclosed |
| US-20090137393-A1 | 2,4,6-TRIALKYLPHENYL SUBSTITUTED CYCLOPENTANE-1,3-DIONE | BAYER CROPSCIENCE AG (DE) | 2009-05-28 | — | — | US | disclosed |
| US-20090137393-A1 | 2,4,6-TRIALKYLPHENYL SUBSTITUTED CYCLOPENTANE-1,3-DIONE | BAYER CROPSCIENCE AG (DE) | 2009-05-28 | — | — | US | disclosed |
| WO-2007080066-A2 | 2,4,6-TRIALKYLPHENYL SUBSTITUTED CYCLOPENTANE-1,3-DIONE | BAYER CROPSCIENCE AG (DE) | 2007-07-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090137393-A1 | 2,4,6-TRIALKYLPHENYL SUBSTITUTED CYCLOPENTANE-1,3-DIONE | DDT, CYP1B1, CNPY2 | TAS1R3 2080/4885TAS1R1 2183/4885TAS1R2 2048/4885 |
| US-20120238450-A1 | C2-PHENYL-SUBSTITUTED CYCLIC KETONOLS | AKR1C3, AKR1C4, AKR1C2 | TAS1R3 4773/4885TAS1R1 4842/4885TAS1R2 4798/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.