SCHEMBL1019999

SCHEMBL1019999

Cc1cc2[nH]nnc2c([N+](=O)[O-])c1Cl

nearest known ligand 0.52

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
GRIN2D O15399 5/20 0.52
GRIN3B O60391 5/20 0.52
GRIN1 Q05586 5/20 0.52
GRIN2A Q12879 5/20 0.52
GRIN2B Q13224 5/20 0.52
GRIN2C Q14957 5/20 0.52
GRIN3A Q8TCU5 5/20 0.52
MEN1 O00255 1/20 0.43
KMT2A Q03164 1/20 0.43
TSHR P16473 2/20 0.38
ADORA2A P29274 1/20 0.38
ADORA2B P29275 1/20 0.38
DCTPP1 Q9H773 5/20 0.37
ALDH1A1 P00352 3/20 0.34
TDP1 Q9NUW8 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1020577 0.84 KMT2A (0.60) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL9952236 0.81 KMT2A (0.43) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL10398538 0.81 ALDH1A1 (0.44) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL1020447 0.78 MEN1 (0.47) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL10622786 0.78 KMT2A (0.43) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL1023472 0.78 ALDH1A1 (0.44) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL9173550 0.77 KMT2A (0.42) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL8623365 0.77 GRIN2D (0.44) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
Silver SCHEMBL9173544 0.77 KMT2A (0.42) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL3214378 0.74 HSD17B10 (0.38) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2121858-B1 AQUEOUS COATING COMPOSITION HAVING REDUCED PLATE OUT ARKEMA INC (US) 2013-10-16 EP disclosed
CN-101617012-B Aqueous coating composition having reduced plate out ARKEMA 2013-08-28 CN disclosed
US-8450402-B2 Method for reducing plate out of aqueous coating compositions ARKEMA INC. (US) 2013-05-28 US disclosed
US-8450401-B2 Aqueous coating composition having reduced plate out ARKEMA INC. (US) 2013-05-28 US disclosed
CN-101616977-B Method for reducing plate out of aqueous coating compositions DOW GLOBAL TECHNOLOGIES INC US 2012-11-14 CN disclosed
EP-2121824-B1 METHOD FOR REDUCING PLATE OUT OF AQUEOUS COATING COMPOSITIONS ARKEMA INC (US) 2011-01-12 EP disclosed
US-20100324169-A1 AQUEOUS COATING COMPOSITION HAVING REDUCED PLATE OUT DOW GLOBAL TECHNOLOGIES, INC (US) 2010-12-23 US disclosed
US-20100319579-A1 METHOD FOR REDUCING PLATE OUT OF AQUEOUS COATING COMPOSITIONS ARKEMA INC. 2010-12-23 US disclosed
CN-101617012-A Reduce the water-based paint compositions of incrustation DOW GLOBAL TECHNOLOGIES INC 2009-12-30 CN disclosed
CN-101616977-A Be used to reduce the method for the incrustation of water-based paint compositions DOW GLOBAL TECHNOLOGIES INC 2009-12-30 CN disclosed