SCHEMBL1020577

SCHEMBL1020577

Cc1cc2[nH]nnc2c([N+](=O)[O-])c1C

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 4/20 0.60
MEN1 O00255 3/20 0.60
GRIN2D O15399 6/20 0.50
GRIN3B O60391 6/20 0.50
GRIN1 Q05586 6/20 0.50
GRIN2A Q12879 6/20 0.50
GRIN2B Q13224 6/20 0.50
GRIN2C Q14957 6/20 0.50
GRIN3A Q8TCU5 6/20 0.50
ALDH1A1 P00352 4/20 0.39
DCTPP1 Q9H773 2/20 0.39
CYP1A2 P05177 2/20 0.39
SMN1; SMN2 Q16637 2/20 0.39
POLB P06746 1/20 0.39
CYP2C9 P11712 1/20 0.39
HPGD P15428 1/20 0.39
CYP2C19 P33261 1/20 0.39
ADORA2A P29274 1/20 0.39
ADORA2B P29275 1/20 0.39
TDP1 Q9NUW8 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1020447 0.87 MEN1 (0.47) KMT2AMEN1GRIN2DGRIN3BGRIN1
SCHEMBL1019999 0.84 GRIN2D (0.52) KMT2AMEN1GRIN2DGRIN3BGRIN1
SCHEMBL9952236 0.84 KMT2A (0.43) KMT2AMEN1GRIN2DGRIN3BGRIN1
SCHEMBL10622786 0.81 KMT2A (0.43) KMT2AMEN1GRIN2DGRIN3BGRIN1
SCHEMBL1023472 0.80 ALDH1A1 (0.44) KMT2AMEN1GRIN2DGRIN3BGRIN1
Silver SCHEMBL9173544 0.80 KMT2A (0.42) KMT2AMEN1GRIN2DGRIN3BGRIN1
SCHEMBL9173550 0.80 KMT2A (0.42) KMT2AMEN1GRIN2DGRIN3BGRIN1
SCHEMBL10398538 0.77 ALDH1A1 (0.44) KMT2AMEN1GRIN2DGRIN3BGRIN1
SCHEMBL13186667 0.75 MEN1 (1.00) KMT2AMEN1GRIN2DGRIN3BGRIN1
SCHEMBL11407056 0.75 GRIN2D (0.53) KMT2AMEN1GRIN2DGRIN3BGRIN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2121858-B1 AQUEOUS COATING COMPOSITION HAVING REDUCED PLATE OUT ARKEMA INC (US) 2013-10-16 EP disclosed
CN-101617012-B Aqueous coating composition having reduced plate out ARKEMA 2013-08-28 CN disclosed
US-8450402-B2 Method for reducing plate out of aqueous coating compositions ARKEMA INC. (US) 2013-05-28 US disclosed
US-8450401-B2 Aqueous coating composition having reduced plate out ARKEMA INC. (US) 2013-05-28 US disclosed
CN-101616977-B Method for reducing plate out of aqueous coating compositions DOW GLOBAL TECHNOLOGIES INC US 2012-11-14 CN disclosed
EP-2121824-B1 METHOD FOR REDUCING PLATE OUT OF AQUEOUS COATING COMPOSITIONS ARKEMA INC (US) 2011-01-12 EP disclosed
US-20100324169-A1 AQUEOUS COATING COMPOSITION HAVING REDUCED PLATE OUT DOW GLOBAL TECHNOLOGIES, INC (US) 2010-12-23 US disclosed
US-20100319579-A1 METHOD FOR REDUCING PLATE OUT OF AQUEOUS COATING COMPOSITIONS ARKEMA INC. 2010-12-23 US disclosed
CN-101616977-A Be used to reduce the method for the incrustation of water-based paint compositions DOW GLOBAL TECHNOLOGIES INC 2009-12-30 CN disclosed
CN-101617012-A Reduce the water-based paint compositions of incrustation DOW GLOBAL TECHNOLOGIES INC 2009-12-30 CN disclosed
EP-2121858-A2 AQUEOUS COATING COMPOSITION HAVING REDUCED PLATE OUT DOW GLOBAL TECHNOLOGIES INC. (US) 2009-11-25 EP disclosed
WO-2008100608-A2 AQUEOUS COATING COMPOSITION HAVING REDUCED PLATE OUT DOW GLOBAL TECHNOLOGIES, INC (US) 2008-08-21 WO disclosed