Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 9/20 | 0.37 |
| ▸ | CCR1 | P32246 | 1/20 | 0.33 |
| ▸ | CCR5 | P51681 | 1/20 | 0.33 |
| ▸ | CCR8 | P51685 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31610186 | 1.00 | EGFR (0.37) | EGFRCCR1CCR5CCR8CYP1A2 | |
| SCHEMBL2843194 | 0.76 | EGFR (0.47) | EGFRCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL8404389 | 0.76 | CCR1 (0.39) | EGFRCCR1CCR5CCR8CYP1A2 | |
| SCHEMBL24495971 | 0.74 | CCR1 (0.32) | CCR1CCR5CCR8 | |
| SCHEMBL18266950 | 0.74 | CCR1 (0.58) | CCR1CCR5CCR8CYP1A2 | |
| Benzene SCHEMBL27961712 | 0.74 | EGFR (0.45) | EGFRCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL22915040 | 0.73 | EGFR (0.34) | EGFR | |
| SCHEMBL24464882 | 0.73 | NQO2 (0.41) | EGFR | |
| SCHEMBL24857275 | 0.71 | EGFR (0.37) | EGFR | |
| SCHEMBL3239463 | 0.71 | EGFR (0.37) | EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023110138-A1 | INHIBITORS OF TRANSGLUTAMINASES | ZEDIRA GMBH (DE) | 2023-06-22 | — | — | WO | disclosed |
| WO-2016118823-A1 | PTERIDINE DIONE MONOCARBOXYLATE TRANSPORTER INHIBITORS | THE SCRIPPS RESEARCH INSTITUTE (US) | 2016-07-28 | — | — | WO | disclosed |
| WO-2016118822-A1 | CHROMENONE INHIBITORS OF MONOCARBOXYLATE TRANSPORTERS | THE SCRIPPS RESEARCH INSTITUTE (US) | 2016-07-28 | — | — | WO | disclosed |
| US-20120030841-A1 | Isoxazoline compounds for combating invertebrate pests | BASF SE (DE) | 2012-02-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120030841-A1 | Isoxazoline compounds for combating invertebrate pests | PRDX5, PRDX1, PRDX2 | EGFR 4875/4885CCR1 4384/4885CCR5 3366/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.