⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL84554 | 1.00 | — | — | |
| SCHEMBL9969577 | 1.00 | — | — | |
| Bromide SCHEMBL9248120 | 0.97 | — | — | |
| SCHEMBL13412378 | 0.97 | — | — | |
| SCHEMBL300796 | 0.92 | — | — | |
| SCHEMBL8440543 | 0.91 | ALDH1A1 (0.35) | — | |
| Benzene SCHEMBL9215717 | 0.89 | SLC6A3 (0.40) | — | |
| Tetrahydrofuran SCHEMBL8438362 | 0.88 | ALDH1A1 (0.36) | — | |
| SCHEMBL838994 | 0.83 | — | — | |
| Allyl Alcohol SCHEMBL27901565 | 0.82 | PTPN1 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 90 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4169924-A2 | SYNTHESIS OF HALICHONDRINS | President And Fellows Of Harvard College (US) | 2023-04-26 | — | — | EP | disclosed |
| US-9353218-B2 | Kit for multifunctional compounds forming crosslinked biomaterials | ANGIOTECH PHARMACEUTICALS, INC. | 2016-05-31 | — | — | US | disclosed |
| US-9353218-B2 | Kit for multifunctional compounds forming crosslinked biomaterials | ANGIOTECH PHARMACEUTICALS, INC. | 2016-05-31 | — | — | US | disclosed |
| US-8841092-B2 | Reversible natural product glycosyltransferase-catalyzed reactions, compounds and related methods | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2014-09-23 | — | — | US | disclosed |
| US-20130289235-A1 | MULTIFUNCTIONAL COMPOUNDS FOR FORMING CROSSLINKED BIOMATERIALS AND METHODS OF PREPARATION AND USE | ANGIOTECH PHARMACEUTICALS, INC. (CA) | 2013-10-31 | — | — | US | disclosed |
| US-20130289235-A1 | MULTIFUNCTIONAL COMPOUNDS FOR FORMING CROSSLINKED BIOMATERIALS AND METHODS OF PREPARATION AND USE | ANGIOTECH PHARMACEUTICALS, INC. (CA) | 2013-10-31 | — | — | US | disclosed |
| US-20130224276-A1 | COMPOSITIONS AND METHODS FOR COATING MEDICAL IMPLANTS | ANGIOTECH INTERNATIONAL AG (CH) | 2013-08-29 | — | — | US | disclosed |
| US-20130224276-A1 | COMPOSITIONS AND METHODS FOR COATING MEDICAL IMPLANTS | ANGIOTECH INTERNATIONAL AG (CH) | 2013-08-29 | — | — | US | disclosed |
| US-8486437-B2 | Multifunctional compounds for forming crosslinked biomaterials and methods of preparation and use | ANGIOTECH PHARMACEUTICALS (US), INC. (US) | 2013-07-16 | — | — | US | disclosed |
| US-8486437-B2 | Multifunctional compounds for forming crosslinked biomaterials and methods of preparation and use | ANGIOTECH PHARMACEUTICALS (US), INC. (US) | 2013-07-16 | — | — | US | disclosed |
| US-20070196421-A1 | Soft tissue implants and drug combination compositions, and use thereof | ANGIOTECH INTERNATIONAL AG (CH) | 2007-08-23 | — | — | US | disclosed |
| US-20070196421-A1 | Soft tissue implants and drug combination compositions, and use thereof | ANGIOTECH INTERNATIONAL AG (CH) | 2007-08-23 | — | — | US | disclosed |
| US-20070198063-A1 | Electrical devices and anti-scarring drug combinations | HUNTER WILLIAM L | 2007-08-23 | — | — | US | disclosed |
| WO-2007089878-A2 | SUTURES AND ANTI-SCARRING AGENTS | ANGIOTECH PHARMACEUTICALS, INC. (CA) | 2007-08-09 | — | — | WO | disclosed |
| US-7241736-B2 | spider, silkworm or other silk as a fibrosing agent; induce adhesion or fibrosis in the walls of the diverticula or facilitate \"filling\" of the diverticula in situ; thus obliterating the lumen of the diverticula and relieving symptoms | ANGIOTECH INTERNATIONAL AG (CH) | 2007-07-10 | — | — | US | disclosed |
| US-7241736-B2 | spider, silkworm or other silk as a fibrosing agent; induce adhesion or fibrosis in the walls of the diverticula or facilitate \"filling\" of the diverticula in situ; thus obliterating the lumen of the diverticula and relieving symptoms | ANGIOTECH INTERNATIONAL AG (CH) | 2007-07-10 | — | — | US | disclosed |
| WO-2007041677-A9 | SOFT TISSUE IMPLANTS AND DRUG COMBINATION COMPOSITIONS, AND USE THEREOF | COMBINATORX INC (US) | 2007-05-31 | — | — | WO | disclosed |
| WO-2007041463-A2 | ELECTRICAL DEVICES AND ANTI-SCARRING DRUG COMBINATIONS | COMBINATORX, INCORPORATED (US) | 2007-04-12 | — | — | WO | disclosed |
| US-7166570-B2 | Treating varicose or veins by injecting a composition silk made of polyalkylene oxide-polyester block copolymer into the lumen of a vein; anchoring implantable medical devices into or onto biological tissue | ANGIOTECH INTERNATIONAL AG (CH) | 2007-01-23 | — | — | US | disclosed |
| US-7166570-B2 | Treating varicose or veins by injecting a composition silk made of polyalkylene oxide-polyester block copolymer into the lumen of a vein; anchoring implantable medical devices into or onto biological tissue | ANGIOTECH INTERNATIONAL AG (CH) | 2007-01-23 | — | — | US | disclosed |