Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 4/20 | 0.35 |
| ▸ | DYRK1A | Q13627 | 4/20 | 0.35 |
| ▸ | WNT1 | P04628 | 3/20 | 0.35 |
| ▸ | SCN3A | Q9NY46 | 2/20 | 0.34 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.34 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.34 |
| ▸ | DHODH | Q02127 | 2/20 | 0.34 |
| ▸ | PSMB8 | P28062 | 2/20 | 0.33 |
| ▸ | IKBKB | O14920 | 2/20 | 0.32 |
| ▸ | CHUK | O15111 | 1/20 | 0.32 |
| ▸ | ATR | Q13535 | 1/20 | 0.32 |
| ▸ | JAK2 | O60674 | 2/20 | 0.32 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.32 |
| ▸ | FLT3 | P36888 | 2/20 | 0.32 |
| ▸ | AAK1 | Q2M2I8 | 2/20 | 0.32 |
| ▸ | KIT | P10721 | 1/20 | 0.32 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.32 |
| ▸ | FLT1 | P17948 | 1/20 | 0.32 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.32 |
| ▸ | JAK1 | P23458 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13258564 | 0.80 | DHODH (0.35) | GSK3BDYRK1AWNT1SCN3ASCN9A | |
| SCHEMBL13258563 | 0.79 | SCN3A (0.35) | GSK3BDYRK1AWNT1SCN3ASCN9A | |
| SCHEMBL12403439 | 0.78 | SCN3A (0.47) | GSK3BDYRK1AWNT1SCN3ASCN9A | |
| SCHEMBL12403445 | 0.77 | SCN3A (0.37) | GSK3BDYRK1AWNT1SCN3ASCN9A | |
| SCHEMBL12405016 | 0.77 | DHODH (0.39) | GSK3BDYRK1AWNT1SCN3ASCN9A | |
| SCHEMBL12403437 | 0.76 | DHODH (0.43) | SCN3ASCN9ADHODHPSMB8IKBKB | |
| SCHEMBL10201555 | 0.76 | DHODH (0.43) | SCN3ASCN9ADHODHPSMB8IKBKB | |
| SCHEMBL12406273 | 0.75 | PTGES (0.38) | GSK3BDYRK1AWNT1SCN3ASCN9A | |
| SCHEMBL10223087 | 0.71 | PSMB8 (0.47) | SCN3ASCN9ASCN10ADHODHPSMB8 | |
| SCHEMBL20966403 | 0.71 | PSMB8 (0.47) | SCN3ASCN9ASCN10ADHODHPSMB8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012018325-A1 | HEPATITIS C VIRUS INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2012-02-09 | — | — | WO | disclosed |