SCHEMBL10201731

SCHEMBL10201731

CN(C)c1ccc(/C=C2\C(=O)N(Cc3ccccc3)c3ccccc32)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
MAPT P10636 17/20 1.00
APP P05067 15/20 1.00
SNCA P37840 15/20 1.00
ALDH1A1 P00352 3/20 0.58
L3MBTL1 Q9Y468 2/20 0.58
MEN1 O00255 2/20 0.58
KMT2A Q03164 2/20 0.58
ALPL P05186 1/20 0.58
ALPI P09923 1/20 0.58
ALPG P10696 1/20 0.58
TDP1 Q9NUW8 1/20 0.58
PIM1 P11309 1/20 0.57
RAB9A P51151 1/20 0.57
SMN1; SMN2 Q16637 1/20 0.57
NPSR1 Q6W5P4 1/20 0.57
GPR35 Q9HC97 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7680134 0.87 MAPT (0.76) MAPTAPPSNCAALDH1A1NPSR1
SCHEMBL7680137 0.87 MAPT (0.76) MAPTAPPSNCAALDH1A1NPSR1
SCHEMBL14589615 0.86 MAPT (0.76) MAPTAPPSNCAALDH1A1MEN1
SCHEMBL10202002 0.82 MAPT (0.70) MAPTAPPSNCAALDH1A1L3MBTL1
SCHEMBL6001665 0.79 MAPT (1.00) MAPTAPPSNCAALDH1A1MEN1
SCHEMBL396972 0.79 ALDH1A1 (0.72) MAPTAPPSNCAALDH1A1NPSR1
SCHEMBL14589616 0.79 MAPT (1.00) MAPTAPPSNCAALDH1A1MEN1
SCHEMBL396971 0.79 ALDH1A1 (0.72) MAPTAPPSNCAALDH1A1NPSR1
SCHEMBL14589628 0.79 MAPT (0.65) MAPTAPPSNCAALDH1A1MEN1
SCHEMBL7672470 0.79 APP (0.65) MAPTAPPSNCAALDH1A1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1744212-B1 Photosensitive composition FUJIFILM CORP (JP) 2012-01-11 EP disclosed
US-20070015087-A1 Photosensitive composition FUJI PHOTO FILM CO., LTD. 2007-01-18 US disclosed
US-20070015087-A1 Photosensitive composition FUJI PHOTO FILM CO., LTD. 2007-01-18 US disclosed
EP-1744212-A2 Photosensitive composition Fuji Photo Film Co., Ltd. (JP) 2007-01-17 EP disclosed