SCHEMBL10202002

SCHEMBL10202002

CN(C)c1ccc(/C=C2\C(=O)N(Cc3ccccc3)c3cc4c(cc32)CCCC4)cc1

nearest known ligand 0.70

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
MAPT P10636 15/20 0.70
APP P05067 13/20 0.70
SNCA P37840 13/20 0.70
ALDH1A1 P00352 3/20 0.50
MEN1 O00255 3/20 0.50
KMT2A Q03164 3/20 0.50
L3MBTL1 Q9Y468 2/20 0.50
ALPL P05186 1/20 0.50
ALPI P09923 1/20 0.50
ALPG P10696 1/20 0.50
TDP1 Q9NUW8 1/20 0.50
RAB9A P51151 1/20 0.49
SMN1; SMN2 Q16637 1/20 0.49
NPSR1 Q6W5P4 1/20 0.49
GPR35 Q9HC97 1/20 0.49
PIM1 P11309 1/20 0.49
KDM4E B2RXH2 1/20 0.48
EP300 Q09472 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10201731 0.82 MAPT (1.00) MAPTAPPSNCAALDH1A1MEN1
SCHEMBL10203230 0.71 MAPT (0.45) MAPTAPPSNCAALDH1A1MEN1
SCHEMBL7680134 0.70 MAPT (0.76) MAPTAPPSNCAALDH1A1NPSR1
SCHEMBL7680137 0.70 MAPT (0.76) MAPTAPPSNCAALDH1A1NPSR1
SCHEMBL14589625 0.69 MAPT (0.58) MAPTAPPSNCAALDH1A1MEN1
SCHEMBL14589615 0.69 MAPT (0.76) MAPTAPPSNCAALDH1A1MEN1
SCHEMBL3454022 0.69 ALDH1A1 (0.80) MAPTAPPSNCAALDH1A1MEN1
SCHEMBL14589626 0.68 MAPT (0.48) MAPTAPPSNCAALDH1A1MEN1
SCHEMBL8372680 0.67 MAPT (0.69) MAPTAPPSNCAALDH1A1MEN1
SCHEMBL14589623 0.67 MAPT (0.55) MAPTAPPSNCAALDH1A1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1744212-B1 Photosensitive composition FUJIFILM CORP (JP) 2012-01-11 EP disclosed
US-20070015087-A1 Photosensitive composition FUJI PHOTO FILM CO., LTD. 2007-01-18 US disclosed
US-20070015087-A1 Photosensitive composition FUJI PHOTO FILM CO., LTD. 2007-01-18 US disclosed
EP-1744212-A2 Photosensitive composition Fuji Photo Film Co., Ltd. (JP) 2007-01-17 EP disclosed