Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | DPP4 | P27487 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10203108 | 1.00 | POLB (0.38) | POLBDPP4KMT2A | |
| SCHEMBL10202105 | 0.83 | CYP1A2 (0.40) | DPP4 | |
| SCHEMBL10202113 | 0.81 | LMNA (0.38) | DPP4 | |
| SCHEMBL10202110 | 0.81 | HTT (0.39) | POLB | |
| SCHEMBL16995151 | 0.79 | DPP4 (0.35) | DPP4 | |
| SCHEMBL16518666 | 0.79 | DPP4 (0.35) | DPP4 | |
| SCHEMBL10202323 | 0.79 | DPP4 (0.35) | DPP4 | |
| SCHEMBL10202119 | 0.79 | DPP4 (0.34) | DPP4 | |
| SCHEMBL10202326 | 0.79 | USP2 (0.38) | DPP4 | |
| SCHEMBL10203871 | 0.78 | ALDH1A1 (0.37) | DPP4KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012061552-A1 | NOVEL INHIBITORS OF HEPATITIS C VIRUS | THERAVANCE, INC. (US) | 2012-05-10 | — | — | WO | disclosed |