SCHEMBL1020252

SCHEMBL1020252

O=C(Cl)c1ccc(N=Nc2ccccc2)cc1

nearest known ligand 0.69

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TRPA1 O75762 1/20 0.69
MAPT P10636 11/20 0.58
RAB9A P51151 6/20 0.58
L3MBTL1 Q9Y468 2/20 0.58
CASP3 P42574 1/20 0.58
SENP8 Q96LD8 1/20 0.58
SENP7 Q9BQF6 1/20 0.58
SENP6 Q9GZR1 1/20 0.58
ALDH1A1 P00352 4/20 0.52
MEN1 O00255 9/20 0.52
KMT2A Q03164 9/20 0.52
NPC1 O15118 6/20 0.52
HTT P42858 4/20 0.49
KDM4E B2RXH2 2/20 0.49
LMNA P02545 1/20 0.49
SMN1; SMN2 Q16637 4/20 0.48
MAPK1 P28482 5/20 0.48
TDP1 Q9NUW8 4/20 0.48
POLB P06746 2/20 0.48
HSP90AA1 P07900 2/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1020251 1.00 TRPA1 (0.69) TRPA1MAPTRAB9AL3MBTL1CASP3
SCHEMBL2202425 0.91 TRPA1 (0.54) TRPA1MAPTRAB9AL3MBTL1CASP3
SCHEMBL2263327 0.91 TRPA1 (0.54) TRPA1MAPTRAB9AL3MBTL1CASP3
Azobenzene SCHEMBL27880955 0.90 TRPA1 (0.57) TRPA1MAPTRAB9AL3MBTL1CASP3
SCHEMBL8731400 0.86 TRPA1 (0.53) TRPA1MAPTRAB9AL3MBTL1CASP3
SCHEMBL11596733 0.84 TRPA1 (0.50) TRPA1MAPTRAB9AL3MBTL1CASP3
SCHEMBL168297 0.82 TRPA1 (1.00) TRPA1MAPTRAB9AL3MBTL1CASP3
SCHEMBL20307199 0.82 TRPA1 (1.00) TRPA1MAPTRAB9AL3MBTL1CASP3
SCHEMBL3361521 0.82 TRPA1 (1.00) TRPA1MAPTRAB9AL3MBTL1CASP3
SCHEMBL384410 0.82 TRPA1 (1.00) TRPA1MAPTRAB9AL3MBTL1CASP3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 136 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118994694-A Light-gating covalent organic framework film and preparation method thereof 天津大学浙江研究院 2024-11-22 CN claimed
US-20240383170-A1 FLEXIBLE AND SMART WOOD WITH RESPONSIVE FUNCTION, PREPARATION METHOD THEREOF AND ACTUATOR NANJING FORESTRY UNIVERSITY (CN) 2024-11-21 US claimed
WO-2024234393-A1 FLEXIBLE INTELLIGENT WOOD HAVING RESPONSE FUNCTION, ACTUATOR, AND MANUFACTURING METHOD 南京林业大学 2024-11-21 WO claimed
CN-118852565-A Photo-responsive covalent organic framework nano sheet and preparation method thereof, photo-responsive covalent organic framework composite film and preparation method and application thereof 天津大学 2024-10-29 CN claimed
CN-116373056-B Flexible intelligent wood with responsiveness function, actuator and preparation method 南京林业大学 2023-12-12 CN claimed
CN-112826791-B Light-operated hydrogel microneedle array patch and preparation method thereof 中国药科大学 2023-11-03 CN claimed
CN-116916918-A Arilanolo for the treatment of niemann pick disease type C in patients with ER-type missense mutations 泽维拉丹麦股份有限公司 2023-10-20 CN claimed
CN-112844316-B Azophenyl photoresponse complexing adsorbent and preparation method and application thereof 南京工业大学 2023-01-24 CN claimed
CN-115304624-A Enoxacin-azobenzene antibacterial compound with photoresponse and preparation method thereof 西北工业大学 2022-11-08 CN claimed
CN-114133547-B Light-operated bonding-debonding underwater hyperbranched adhesive and preparation method and application thereof 江南大学 2022-07-19 CN claimed
CN-114133547-A Light-operated bonding-debonding underwater hyperbranched adhesive and preparation method and application thereof 江南大学 2022-03-04 CN claimed
CN-112844316-A Azophenyl photoresponse complexing adsorbent and preparation method and application thereof 南京工业大学 2021-05-28 CN claimed
CN-112826791-A Light-controlled hydrogel microneedle array patch and preparation method thereof 中国药科大学 2021-05-25 CN claimed
CN-111228506-A Preparation and use methods of near-infrared response drug sustained release system based on up-conversion nanoparticles @ metal organic framework 西北工业大学 2020-06-05 CN claimed
US-4113431-A CELLULOSE REACTED WITH A BENZOYLATING AGENT SHIKIBO LIMITED (JP) 1978-09-12 US claimed
EP-4724035-A1 COMPOUNDS ATTACHABLE TO KERATINOUS TISSUES BIC Inc. (CA) 2026-04-15 EP disclosed
EP-4724432-A1 HYDROGENATED GENIPIN DERIVATIVES ATTACHABLE TO KERATINOUS TISSUES BIC Inc. (CA) 2026-04-15 EP disclosed
US-4113431-A CELLULOSE REACTED WITH A BENZOYLATING AGENT SHIKIBO LIMITED (JP) 1978-09-12 US disclosed
US-4069224-A N-(PYRIDYLALKYL)BENZAMIDES, IMPROVE PRODUCTION OF PROSTAGLANDINS IN MAMMALS THE UPJOHN COMPANY (US) 1978-01-17 US disclosed
US-4044051-A TREATMENT OF SKIN DISORDERS HOFFMANN-LA ROCHE INC. (US) 1977-08-23 US disclosed