SCHEMBL2202425

SCHEMBL2202425

O=C(Cl)c1ccc(N=Nc2ccc(C(=O)Cl)cc2)cc1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TRPA1 O75762 1/20 0.54
NPC1 O15118 9/20 0.50
MAPT P10636 8/20 0.50
RAB9A P51151 8/20 0.50
SMN1; SMN2 Q16637 4/20 0.50
TDP1 Q9NUW8 3/20 0.50
MAPK1 P28482 2/20 0.50
STAT3 P40763 1/20 0.50
STAT1 P42224 1/20 0.50
ALDH1A1 P00352 3/20 0.46
KMT2A Q03164 5/20 0.45
MEN1 O00255 4/20 0.45
POLB P06746 2/20 0.45
L3MBTL1 Q9Y468 2/20 0.45
KDM4E B2RXH2 2/20 0.45
CASP3 P42574 1/20 0.45
SENP8 Q96LD8 1/20 0.45
SENP7 Q9BQF6 1/20 0.45
SENP6 Q9GZR1 1/20 0.45
CD69 Q07108 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2263327 1.00 TRPA1 (0.54) TRPA1NPC1MAPTRAB9ASMN1; SMN2
SCHEMBL1020251 0.91 TRPA1 (0.69) TRPA1NPC1MAPTRAB9ASMN1; SMN2
SCHEMBL1020252 0.91 TRPA1 (0.69) TRPA1NPC1MAPTRAB9ASMN1; SMN2
SCHEMBL18867234 0.89 MAPT (0.68) TRPA1NPC1MAPTRAB9ASMN1; SMN2
SCHEMBL18833038 0.85 TRPA1 (0.42) TRPA1NPC1MAPTRAB9ASMN1; SMN2
SCHEMBL18867233 0.84 GSK3B (0.50) TRPA1NPC1MAPTRAB9ASMN1; SMN2
SCHEMBL11596733 0.84 TRPA1 (0.50) TRPA1NPC1MAPTRAB9ASMN1; SMN2
SCHEMBL7889532 0.84 NPC1 (0.71) NPC1MAPTRAB9ATDP1MAPK1
SCHEMBL2682067 0.84 NPC1 (0.71) NPC1MAPTRAB9ATDP1MAPK1
SCHEMBL8733390 0.84 CES2 (0.53) MAPTRAB9ASMN1; SMN2MAPK1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 117 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250332075-A1 POLYAMIDE MICROCAPSULES FIRMENICH & CIE (CH) 2025-10-30 US claimed
US-20250312763-A1 POLYAMIDE MICROCAPSULES FIRMENICH SA (CH) 2025-10-09 US claimed
CN-117024444-B Fluorescent probe molecule, preparation method and application thereof 华中科技大学 2025-06-03 CN claimed
EP-4522324-A1 POLYAMIDE MICROCAPSULES Firmenich SA (CH) 2025-03-19 EP claimed
EP-4522325-A1 POLYAMIDE MICROCAPSULES Firmenich SA (CH) 2025-03-19 EP claimed
CN-117717902-A Preparation method and application of covalent organic framework nanofiltration membrane 天津大学 2024-03-19 CN claimed
CN-117563561-A Photosensitive lithium ion selective adsorption material and preparation method thereof 厦门大学 2024-02-20 CN claimed
WO-2023217589-A1 POLYAMIDE MICROCAPSULES FIRMENICH SA (CH) 2023-11-16 WO claimed
WO-2023217590-A1 POLYAMIDE MICROCAPSULES FIRMENICH SA (CH) 2023-11-16 WO claimed
CN-117024444-A Fluorescent probe molecule, preparation method and application thereof 华中科技大学 2023-11-10 CN claimed
US-20180236408-A1 A PREPARATION METHOD FOR TRIPTYL POLYMER SEPARATION MEMBRANE NANJING TECH UNIVERSITY (CN) 2018-08-23 US claimed
EP-3323500-A1 MANUFACTURING METHOD FOR TRIPTYCENE POLYMER CARRIER FILM Nanjing Tech University (CN) 2018-05-23 EP claimed
US-9890351-B2 Encapsulates THE PROCTER & GAMBLE COMPANY (US) 2018-02-13 US claimed
US-9708469-B2 Photoisomerizing polymers INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2017-07-18 US claimed
US-20170158828-A1 PHOTOISOMERIZING POLYMERS INTERNATIONAL BUSINESS MACHINES CORPORATION 2017-06-08 US claimed
EP-2741731-B1 ENCAPSULATES PROCTER & GAMBLE (US) 2017-05-17 EP claimed
US-20160355639-A1 PHOTOISOMERIZING POLYMERS INTERNATIONAL BUSINESS MACHINES CORPORATION 2016-12-08 US claimed
EP-2741731-A1 ENCAPSULATES The Procter and Gamble Company (US) 2014-06-18 EP claimed
US-20130039962-A1 ENCAPSULATES ENCAPSYS, LLC 2013-02-14 US claimed
WO-2013022949-A1 ENCAPSULATES THE PROCTER & GAMBLE COMPANY (US) 2013-02-14 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130039962-A1 ENCAPSULATES ABCB4, PPIB, FLNB TRPA1 942/4885NPC1 3234/4885MAPT 1158/4885
US-20250332075-A1 POLYAMIDE MICROCAPSULES PSAP, POLI, PGA5 TRPA1 966/4885NPC1 4112/4885MAPT 1026/4885
US-20250312763-A1 POLYAMIDE MICROCAPSULES PSAP, PPHLN1, PARG TRPA1 755/4885NPC1 4113/4885MAPT 1421/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.