SCHEMBL1020448

SCHEMBL1020448

CCCCc1ccc2[nH]nnc2c1O

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TYR P14679 3/20 0.41
ELANE P08246 4/20 0.36
CTSG P08311 4/20 0.36
ALOX5 P09917 2/20 0.36
PTGS2 P35354 1/20 0.36
MEN1 O00255 1/20 0.35
TP53 P04637 1/20 0.35
CYP3A4 P08684 1/20 0.35
MAPT P10636 1/20 0.35
ALOX15 P16050 1/20 0.35
TSHR P16473 1/20 0.35
HTT P42858 1/20 0.35
KMT2A Q03164 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
CCNB2 O95067 1/20 0.33
CCNE2 O96020 1/20 0.33
INSR P06213 1/20 0.33
CDK1 P06493 1/20 0.33
CFTR P13569 1/20 0.33
CCNB1 P14635 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8768179 0.95 TYR (0.46) TYRELANECTSGALOX5PTGS2
SCHEMBL11620585 0.94 TYR (0.49) TYRELANECTSGALOX5PTGS2
SCHEMBL30629353 0.83 GABRA1 (0.41)
SCHEMBL28971644 0.83 TYR (0.34) TYRTP53CYP3A4MAPTTSHR
SCHEMBL574848 0.82 HTR2C (0.36)
SCHEMBL29565084 0.80 ELANE (0.40) TYRELANECTSGALOX5PTGS2
SCHEMBL8149251 0.80 ELANE (0.40) TYRELANECTSGALOX5PTGS2
SCHEMBL5465510 0.79 DPP4 (0.33) TYRTP53TSHR
SCHEMBL11074239 0.78 ELANE (0.41) TYRELANECTSGMEN1MAPT
SCHEMBL18209097 0.78 TYR (0.32) TYRELANECTSGCCNB2CCNE2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2121858-B1 AQUEOUS COATING COMPOSITION HAVING REDUCED PLATE OUT ARKEMA INC (US) 2013-10-16 EP disclosed
CN-101617012-B Aqueous coating composition having reduced plate out ARKEMA 2013-08-28 CN disclosed
US-8450401-B2 Aqueous coating composition having reduced plate out ARKEMA INC. (US) 2013-05-28 US disclosed
US-8450402-B2 Method for reducing plate out of aqueous coating compositions ARKEMA INC. (US) 2013-05-28 US disclosed
CN-101616977-B Method for reducing plate out of aqueous coating compositions DOW GLOBAL TECHNOLOGIES INC US 2012-11-14 CN disclosed
EP-2121824-B8 METHOD FOR REDUCING PLATE OUT OF AQUEOUS COATING COMPOSITIONS ARKEMA INC (US) 2011-02-23 EP disclosed
EP-2121824-B1 METHOD FOR REDUCING PLATE OUT OF AQUEOUS COATING COMPOSITIONS ARKEMA INC (US) 2011-01-12 EP disclosed
US-20100324169-A1 AQUEOUS COATING COMPOSITION HAVING REDUCED PLATE OUT DOW GLOBAL TECHNOLOGIES, INC (US) 2010-12-23 US disclosed
US-20100319579-A1 METHOD FOR REDUCING PLATE OUT OF AQUEOUS COATING COMPOSITIONS ARKEMA INC. 2010-12-23 US disclosed
CN-101616977-A Be used to reduce the method for the incrustation of water-based paint compositions DOW GLOBAL TECHNOLOGIES INC 2009-12-30 CN disclosed
CN-101617012-A Reduce the water-based paint compositions of incrustation DOW GLOBAL TECHNOLOGIES INC 2009-12-30 CN disclosed
EP-2121858-A2 AQUEOUS COATING COMPOSITION HAVING REDUCED PLATE OUT DOW GLOBAL TECHNOLOGIES INC. (US) 2009-11-25 EP disclosed
EP-2121824-A2 METHOD FOR REDUCING PLATE OUT OF AQUEOUS COATING COMPOSITIONS DOW GLOBAL TECHNOLOGIES INC. (US) 2009-11-25 EP disclosed
WO-2008100608-A2 AQUEOUS COATING COMPOSITION HAVING REDUCED PLATE OUT DOW GLOBAL TECHNOLOGIES, INC (US) 2008-08-21 WO disclosed
WO-2008100607-A2 METHOD FOR REDUCING PLATE OUT OF AQUEOUS COATING COMPOSITIONS DOW GLOBAL TECHNOLOGIES, INC (US) 2008-08-21 WO disclosed
EP-0011460-B1 PEROXYGEN BLEACHING AND COMPOSITIONS THEREFOR FMC Corporation (US) 1982-09-29 EP disclosed
US-4215003-A INCLUDING HETEROCYCLIC SULFONATE ESTERS OF AN ALKANE- OR ARYLSULFONIC ACID AS ACTIVATORS; LOW TEMPERATURE FMC CORPORATION (US) 1980-07-29 US disclosed
EP-0011460-A1 Peroxygen bleaching and compositions therefor FMC Corporation (US) 1980-05-28 EP disclosed