Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 4/20 | 0.41 |
| ▸ | CTSG | P08311 | 4/20 | 0.41 |
| ▸ | GCGR | P47871 | 2/20 | 0.38 |
| ▸ | TYR | P14679 | 1/20 | 0.36 |
| ▸ | PDE5A | O76074 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | APAF1 | O14727 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | STAT6 | P42226 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 1/20 | 0.34 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | GFER | P55789 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15020976 | 0.96 | GCGR (0.42) | ELANECTSGGCGRTYRPDE5A | |
| SCHEMBL11666453 | 0.95 | ELANE (0.43) | ELANECTSGGCGRTYRLMNA | |
| SCHEMBL15020254 | 0.84 | GCGR (0.43) | ELANECTSGGCGRTYRPDE5A | |
| SCHEMBL991777 | 0.84 | IDO1 (0.36) | LMNAMEN1KMT2AIDO1ALDH1A1 | |
| SCHEMBL27669182 | 0.84 | NR1H2 (0.39) | ELANECTSG | |
| SCHEMBL1938294 | 0.82 | HSD11B1 (0.38) | GCGRKDM4ETLR8 | |
| SCHEMBL15058924 | 0.81 | TRPA1 (0.36) | ELANECTSGTLR8 | |
| SCHEMBL28489734 | 0.80 | KAT8 (0.41) | TYRLMNAKDM4EMEN1MAPT | |
| SCHEMBL2731449 | 0.79 | GABRA1 (0.38) | ELANELMNAKDM4EMEN1POLB | |
| SCHEMBL1020448 | 0.78 | TYR (0.41) | ELANECTSGTYRKDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4469829-A | SOLAR RADIATION RESISTANCE | CHEMISCHE WERKE HULS AG (DE) | 1984-09-04 | — | — | US | disclosed |