Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 12/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 9/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | HTR2B | P41595 | 1/20 | 0.36 |
| ▸ | RIPK3 | Q9Y572 | 1/20 | 0.33 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1021420 | 0.83 | PTGS2 (0.50) | PTGS1PTGS2 | |
| SCHEMBL1022376 | 0.81 | PTGS1 (0.50) | PTGS1PTGS2HTTUSP2ALDH1A1 | |
| SCHEMBL1019980 | 0.79 | PTGS1 (0.48) | PTGS1PTGS2HTTUSP2ALDH1A1 | |
| SCHEMBL1020338 | 0.77 | HTR2A (0.34) | HTR2AHTR2CHTR2B | |
| SCHEMBL1022110 | 0.76 | PTGS1 (0.46) | PTGS1PTGS2HTTUSP2ALDH1A1 | |
| SCHEMBL1020565 | 0.75 | PTGS1 (0.44) | PTGS1PTGS2HTTUSP2ALDH1A1 | |
| SCHEMBL16148107 | 0.74 | PTGS1 (0.43) | PTGS1PTGS2HTTUSP2ALDH1A1 | |
| SCHEMBL1023721 | 0.74 | PTGS2 (0.46) | PTGS2ALDH1A1 | |
| SCHEMBL1023968 | 0.73 | RARB (0.36) | PTGS1PTGS2HTTHTR2A | |
| SCHEMBL1024205 | 0.72 | PTGS1 (0.54) | PTGS1PTGS2HTTUSP2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1841729-B1 | 2-CYCLOPENTEN-1-ONE OXIME DERIVATIVES INHIBITING PRODUCTION OF TNF-ALPHA | AMOREPACIFIC CORP (KR) | 2011-01-12 | — | — | EP | claimed |