Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 3/20 | 0.36 |
| ▸ | RARA | P10276 | 1/20 | 0.36 |
| ▸ | RARG | P13631 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | TYR | P14679 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.34 |
| ▸ | GCGR | P47871 | 2/20 | 0.32 |
| ▸ | CNR2 | P34972 | 3/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | RORC | P51449 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1022770 | 0.84 | MEN1 (0.35) | RARBRARARARGTSHRMEN1 | |
| SCHEMBL1022768 | 0.84 | MEN1 (0.35) | RARBRARARARGTSHRMEN1 | |
| SCHEMBL1021420 | 0.80 | PTGS2 (0.50) | MEN1MAPTKMT2APTGS1PTGS2 | |
| SCHEMBL1021324 | 0.78 | PTGS2 (0.48) | RARBRARARARGPTGS1PTGS2 | |
| SCHEMBL1023688 | 0.75 | PTGS2 (0.51) | RARBRARARARGMEN1HTT | |
| SCHEMBL1022350 | 0.74 | PTGS2 (0.49) | RARBRARARARGPTGS1PTGS2 | |
| SCHEMBL1020604 | 0.73 | PTGS1 (0.47) | HTTPTGS1PTGS2HTR2A | |
| SCHEMBL1023216 | 0.72 | CYP1A2 (0.43) | TSHRKMT2A | |
| SCHEMBL27687397 | 0.71 | MEN1 (0.32) | RARBRARARARGTSHRMEN1 | |
| SCHEMBL1022426 | 0.71 | HSD17B1 (0.47) | RARBRARARARGPTGS1PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1841729-B1 | 2-CYCLOPENTEN-1-ONE OXIME DERIVATIVES INHIBITING PRODUCTION OF TNF-ALPHA | AMOREPACIFIC CORP (KR) | 2011-01-12 | — | — | EP | claimed |