Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RBP4 | P02753 | 15/20 | 0.51 |
| ▸ | AVPR1A | P37288 | 4/20 | 0.48 |
| ▸ | CNR1 | P21554 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL614129 | 0.92 | AVPR1A (0.57) | RBP4AVPR1ACNR1 | |
| SCHEMBL614574 | 0.88 | AVPR1A (0.60) | RBP4AVPR1ACNR1 | |
| SCHEMBL613346 | 0.87 | RBP4 (0.56) | RBP4 | |
| SCHEMBL612849 | 0.86 | RBP4 (0.56) | RBP4 | |
| SCHEMBL614775 | 0.85 | RBP4 (0.53) | RBP4AVPR1ACNR1 | |
| SCHEMBL614158 | 0.84 | AVPR1A (0.58) | RBP4AVPR1ACNR1 | |
| SCHEMBL613550 | 0.83 | RBP4 (0.54) | RBP4AVPR1A | |
| SCHEMBL614646 | 0.82 | RBP4 (0.50) | RBP4AVPR1ACNR1 | |
| Hydrochloric Acid SCHEMBL614973 | 0.82 | RBP4 (0.53) | RBP4AVPR1ACNR1 | |
| Hydrochloric Acid SCHEMBL614718 | 0.81 | RBP4 (0.49) | RBP4AVPR1ACNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120040990-A1 | INDOL-3-Y-CARBONYL-PIPERIDIN AND PIPERAZIN-DERIVATIVES | BISSANTZ CATERINA (FR) | 2012-02-16 | — | — | US | disclosed |
| US-20120040990-A1 | INDOL-3-Y-CARBONYL-PIPERIDIN AND PIPERAZIN-DERIVATIVES | BISSANTZ CATERINA (FR) | 2012-02-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120040990-A1 | INDOL-3-Y-CARBONYL-PIPERIDIN AND PIPERAZIN-DERIVATIVES | AVPR1A, AVPR2, OXTR | RBP4 4183/4885AVPR1A 1/4885CNR1 31/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.