Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 4/20 | 0.42 |
| ▸ | CA2 | P00918 | 4/20 | 0.42 |
| ▸ | CA7 | P43166 | 3/20 | 0.42 |
| ▸ | CA9 | Q16790 | 3/20 | 0.42 |
| ▸ | CA12 | O43570 | 2/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.42 |
| ▸ | CA4 | P22748 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27665453 | 0.81 | TUBB1 (0.35) | CA1CA2CA7CA9CA12 | |
| SCHEMBL4302129 | 0.80 | CA1 (0.55) | CA1CA2CA7CA9CA12 | |
| SCHEMBL630768 | 0.79 | CA1 (0.58) | CA1CA2CA7CA9CA12 | |
| SCHEMBL2094827 | 0.74 | CA1 (0.46) | CA1CA2CA7CA9CA12 | |
| SCHEMBL10578058 | 0.73 | TUBB1 (0.35) | CA1CA2CA7CA9CA12 | |
| SCHEMBL27759581 | 0.73 | TUBB1 (0.33) | CA1CA2CA7CA9CA12 | |
| SCHEMBL196734 | 0.73 | CA1 (0.50) | CA1CA2CA7CA9CA12 | |
| SCHEMBL29387155 | 0.73 | CA1 (0.50) | CA1CA2CA7CA9CA12 | |
| SCHEMBL11016571 | 0.72 | RAB9A (0.34) | CA1CA2CA7CA9CA12 | |
| SCHEMBL5633423 | 0.72 | TUBB1 (0.33) | CA1CA2CA7CA9CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 94 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109678788-A | A kind of 1,2- diaryl indoles, derivative and its synthetic method | 湘潭大学 | 2019-04-26 | — | — | CN | claimed |
| CN-106946781-B | A kind of pyrazoles diphenyl urea analog derivative and its preparation method and application | 合肥工业大学 | 2019-04-19 | — | — | CN | claimed |
| CN-107032965-A | A kind of preparation method of 3 trifluoro-methoxy-phenol | 金凯(辽宁)化工有限公司 | 2017-08-11 | — | — | CN | claimed |
| CN-102797043-B | Medicinal molecular fragment library and construction process thereof | Tianli (Tianjin) Technology Co., Ltd. (CN) | 2015-11-25 | — | — | CN | claimed |
| CN-104262181-A | Preparing method of fluorine-group-containing ethyl 3-(phenyl-1-imine) propionate analogues | SHANGHAI INST TECHNOLOGY | 2015-01-07 | — | — | CN | claimed |
| CN-102797043-A | Medicinal molecular fragment library and construction method thereof | CBB NETWORK CO LTD | 2012-11-28 | — | — | CN | claimed |
| CN-109678788-A | A kind of 1,2- diaryl indoles, derivative and its synthetic method | 湘潭大学 | 2019-04-26 | — | — | CN | disclosed |
| CN-106946781-B | A kind of pyrazoles diphenyl urea analog derivative and its preparation method and application | 合肥工业大学 | 2019-04-19 | — | — | CN | disclosed |
| CN-108047142-A | Heteroaryl compound and its purposes | 阿维拉制药公司 | 2018-05-18 | — | — | CN | disclosed |
| CN-104892485-B | 2 perfluoroalkyl indole derivativeses and its synthetic method | 上海麦克林生化科技有限公司 | 2018-03-23 | — | — | CN | disclosed |
| CN-107108536-A | Biguanide compound and application thereof | 伊谬诺米特医疗有限公司 | 2017-08-29 | — | — | CN | disclosed |
| CN-107098846-A | N- acyl sulfonamides class FBPase inhibitor, its preparation method, pharmaceutical composition and purposes | 中国医学科学院药物研究所 | 2017-08-29 | — | — | CN | disclosed |
| CN-107032965-A | A kind of preparation method of 3 trifluoro-methoxy-phenol | 金凯(辽宁)化工有限公司 | 2017-08-11 | — | — | CN | disclosed |
| CN-1043531-C | Pyrimidine derivatives and a process for production thereof | NOVATIS AG (CH) | 1999-06-02 | — | — | CN | disclosed |
| EP-0862560-A1 | SUBSTITUTED 2-ANILINOPYRIMIDINES USEFUL AS PROTEIN KINASE INHIBITORS | CELLTECH THERAPEUTICS LIMITED (GB) | 1998-09-09 | — | — | EP | disclosed |
| CN-1190962-A | Process for the preparation of substituted 5-hydroxy-oxazolidin-4-one | ZENECA LTD (GB) | 1998-08-19 | — | — | CN | disclosed |
| WO-1997019065-A1 | SUBSTITUTED 2-ANILINOPYRIMIDINES USEFUL AS PROTEIN KINASE INHIBITORS | CELLTECH THERAPEUTICS LIMITED (GB) | 1997-05-29 | — | — | WO | disclosed |
| CN-1092425-A | Indole derivatives, its manufacture method and medicinal use thereof | TORAY INDUSTRIES (JP) | 1994-09-21 | — | — | CN | disclosed |
| CN-1077713-A | Pyrimidine derivatives and preparation method thereof | CIBA GEIGY AG (CH) | 1993-10-27 | — | — | CN | disclosed |
| CN-1074678-A | 1, the 5-benzodiazepine derivatives | GLAXO SPA (IT) | 1993-07-28 | — | — | CN | disclosed |