Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | AKT1 | P31749 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.32 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.32 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.32 |
| ▸ | FAAH | O00519 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2948074 | 0.94 | TSHR (0.50) | TSHRTDP1KMT2AMEN1POLB | |
| SCHEMBL1021356 | 0.89 | TSHR (0.52) | TSHRTDP1KMT2AMEN1POLB | |
| SCHEMBL1021119 | 0.88 | TSHR (0.50) | TSHRTDP1KMT2AMEN1NPC1 | |
| SCHEMBL1021096 | 0.87 | TSHR (0.49) | TSHRTDP1KMT2AMEN1MAPT | |
| SCHEMBL1021522 | 0.86 | TSHR (0.58) | TSHRTDP1KMT2AMEN1POLB | |
| SCHEMBL989495 | 0.86 | TSHR (0.58) | TSHRTDP1POLBRAB9AEPHX1 | |
| SCHEMBL1021566 | 0.86 | TSHR (0.48) | TSHRTDP1EPHX1FAAH | |
| SCHEMBL1024786 | 0.86 | TSHR (0.48) | TSHRTDP1EPHX1FAAH | |
| SCHEMBL1309265 | 0.86 | TSHR (0.48) | TSHRTDP1EPHX1FAAH | |
| SCHEMBL2948077 | 0.84 | TSHR (0.38) | TSHRKMT2AMEN1POLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8053595-B2 | Process for producing isocyanates | ASAHI KASEI CHEMICALS CORPORATION (JP) | 2011-11-08 | — | — | US | disclosed |
| EP-2088137-B1 | A PROCESS FOR PRODUCING ISOCYANATES | ASAHI KASEI CHEMICALS CORP (JP) | 2011-01-12 | — | — | EP | disclosed |