Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 4/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2714144 | 0.86 | CNR2 (0.54) | CNR2SIGMAR1KMT2AMEN1 | |
| SCHEMBL10214778 | 0.82 | TSHR (0.47) | CNR2TSHRLMNASMN1; SMN2SIGMAR1 | |
| SCHEMBL10216685 | 0.76 | CNR2 (0.71) | CNR2KMT2AMEN1 | |
| SCHEMBL13871715 | 0.75 | OPRM1 (0.44) | CNR2TSHRKMT2A | |
| SCHEMBL14003136 | 0.75 | KMT2A (0.47) | CNR2TSHRTP53SMN1; SMN2ALDH1A1 | |
| SCHEMBL10080608 | 0.74 | CNR2 (1.00) | CNR2TSHRLMNAALDH1A1KMT2A | |
| SCHEMBL300369 | 0.74 | CNR2 (1.00) | CNR2TSHRLMNAALDH1A1KMT2A | |
| SCHEMBL300456 | 0.74 | CNR2 (1.00) | CNR2TSHRLMNAALDH1A1KMT2A | |
| SCHEMBL13871328 | 0.74 | CNR2 (1.00) | CNR2TSHRLMNAALDH1A1KMT2A | |
| SCHEMBL10080607 | 0.74 | CNR2 (1.00) | CNR2TSHRLMNAALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1735286-B1 | TETRAHYDRO-INDAZOLE CANNABINOID MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2012-01-04 | — | — | EP | disclosed |