Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | CNR2 | P34972 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.42 |
| ▸ | KCNJ6 | P48051 | 2/20 | 0.41 |
| ▸ | KCNJ5 | P48544 | 2/20 | 0.41 |
| ▸ | KCNJ3 | P48549 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | ADCY1 | Q08828 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.41 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.41 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.41 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2716208 | 0.87 | BTK (0.43) | KMT2ACNR2TP53SMN1; SMN2NPC1 | |
| SCHEMBL13871464 | 0.82 | CNR1 (0.48) | CNR2NPC1ALDH1A1HPGD | |
| SCHEMBL10214778 | 0.79 | TSHR (0.47) | KMT2ACNR2SMN1; SMN2KDM4CNPC1 | |
| SCHEMBL13871470 | 0.77 | HSD11B1 (0.47) | KMT2ACNR2KCNJ6KCNJ5KCNJ3 | |
| SCHEMBL13871472 | 0.77 | CNR2 (0.58) | KMT2ACNR2SMN1; SMN2KCNJ6KCNJ5 | |
| SCHEMBL10214775 | 0.75 | CNR2 (0.58) | KMT2ACNR2TP53SMN1; SMN2ALDH1A1 | |
| SCHEMBL13871715 | 0.74 | OPRM1 (0.44) | KMT2ACNR2KDM4CKCNJ6KCNJ5 | |
| SCHEMBL2718387 | 0.73 | CNR2 (0.48) | CNR2SMN1; SMN2KCNJ6KCNJ5KCNJ3 | |
| SCHEMBL14027869 | 0.72 | TAS1R3 (0.45) | CNR2KDM4C | |
| SCHEMBL14003139 | 0.72 | MAPK1 (0.54) | CNR2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7452997-B2 | Tetrahydro-indazole cannabinoid modulators | JANSSEN PHARMACEUTICA, N.V. (BE) | 2008-11-18 | — | — | US | disclosed |
| US-7452997-B2 | Tetrahydro-indazole cannabinoid modulators | JANSSEN PHARMACEUTICA, N.V. (BE) | 2008-11-18 | — | — | US | disclosed |