Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | SIRT2 | Q8IXJ6 | 5/20 | 0.37 |
| ▸ | SIRT1 | Q96EB6 | 3/20 | 0.36 |
| ▸ | PGR | P06401 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.35 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.35 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.35 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.34 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.34 |
| ▸ | FYN | P06241 | 1/20 | 0.34 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.34 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | CTSS | P25774 | 1/20 | 0.34 |
| ▸ | CTSK | P43235 | 1/20 | 0.34 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1022356 | 0.84 | BRD4 (0.40) | — | |
| SCHEMBL1020035 | 0.84 | ESR1 (0.40) | — | |
| SCHEMBL1021433 | 0.84 | NPC1 (0.36) | CHRNB4CHRNA3MAPTCTSSCTSK | |
| SCHEMBL1021866 | 0.82 | CHRNB4 (0.38) | PGRCHRNB4CHRNA3 | |
| SCHEMBL1022920 | 0.82 | BRD4 (0.42) | TLR8 | |
| SCHEMBL1025827 | 0.81 | PTPN11 (0.44) | — | |
| SCHEMBL1020478 | 0.81 | MAPT (0.45) | KDM4ETP53MAPT | |
| SCHEMBL1021059 | 0.81 | TLR8 (0.40) | PARP10PARP11TLR8CTSSCTSK | |
| SCHEMBL1022880 | 0.81 | BRD4 (0.39) | KDM4ETP53MAPTHTTCTSK | |
| SCHEMBL1021652 | 0.81 | PTGS1 (0.48) | TLR8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1841729-B1 | 2-CYCLOPENTEN-1-ONE OXIME DERIVATIVES INHIBITING PRODUCTION OF TNF-ALPHA | AMOREPACIFIC CORP (KR) | 2011-01-12 | — | — | EP | claimed |