Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 3/20 | 0.48 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.48 |
| ▸ | GCGR | P47871 | 1/20 | 0.40 |
| ▸ | NR5A2 | O00482 | 1/20 | 0.39 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.39 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.38 |
| ▸ | MGLL | Q99685 | 1/20 | 0.37 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | ICMT | O60725 | 3/20 | 0.35 |
| ▸ | GHSR | Q92847 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1021894 | 0.86 | PTGS1 (0.43) | PTGS1PTGS2GHSR | |
| SCHEMBL1020565 | 0.83 | PTGS1 (0.44) | PTGS1PTGS2GCGRGRM2GHSR | |
| SCHEMBL1023950 | 0.83 | PTPN1 (0.42) | PTGS1PTGS2NR5A2NR5A1 | |
| SCHEMBL1021324 | 0.82 | PTGS2 (0.48) | PTGS1PTGS2GCGRGHSR | |
| SCHEMBL1021653 | 0.81 | KDM4E (0.37) | TLR8 | |
| SCHEMBL1020191 | 0.81 | MGLL (0.42) | PTGS1PTGS2GCGRNR5A2NR5A1 | |
| SCHEMBL1020190 | 0.81 | MGLL (0.42) | PTGS1PTGS2GCGRNR5A2NR5A1 | |
| SCHEMBL1022577 | 0.80 | ALDH1A1 (0.43) | NPC1RAB9A | |
| SCHEMBL1020035 | 0.80 | ESR1 (0.40) | PTGS2GCGRMGLLGRM2 | |
| SCHEMBL1022356 | 0.80 | BRD4 (0.40) | PTGS1PTGS2GRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1841729-B1 | 2-CYCLOPENTEN-1-ONE OXIME DERIVATIVES INHIBITING PRODUCTION OF TNF-ALPHA | AMOREPACIFIC CORP (KR) | 2011-01-12 | — | — | EP | claimed |