Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN11 | Q06124 | 2/20 | 0.44 |
| ▸ | KMO | O15229 | 1/20 | 0.42 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.41 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.41 |
| ▸ | RARB | P10826 | 1/20 | 0.40 |
| ▸ | RXRA | P19793 | 2/20 | 0.39 |
| ▸ | RXRB | P28702 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CD74 | P04233 | 1/20 | 0.38 |
| ▸ | MIF | P14174 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1072869 | 0.85 | CYP4F2 (0.46) | — | |
| SCHEMBL1020778 | 0.84 | PTPN11 (0.42) | PTPN11KMONR1H4LTB4R2RARB | |
| SCHEMBL1020777 | 0.84 | PTPN11 (0.42) | PTPN11KMONR1H4LTB4R2RARB | |
| SCHEMBL1021752 | 0.84 | RARB (0.55) | RARBRXRAKMT2A | |
| SCHEMBL1020035 | 0.83 | ESR1 (0.40) | — | |
| SCHEMBL1021653 | 0.81 | KDM4E (0.37) | — | |
| SCHEMBL1021866 | 0.81 | CHRNB4 (0.38) | — | |
| SCHEMBL1021433 | 0.80 | NPC1 (0.36) | — | |
| SCHEMBL1022356 | 0.80 | BRD4 (0.40) | — | |
| SCHEMBL1022920 | 0.78 | BRD4 (0.42) | KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1841729-B1 | 2-CYCLOPENTEN-1-ONE OXIME DERIVATIVES INHIBITING PRODUCTION OF TNF-ALPHA | AMOREPACIFIC CORP (KR) | 2011-01-12 | — | — | EP | claimed |