Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.36 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.36 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.36 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.36 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.36 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | PARP1 | P09874 | 2/20 | 0.35 |
| ▸ | RAD52 | P43351 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3392523 | 0.79 | POLB (0.34) | POLBCYP2C9ALDH1A1IDO1LMNA | |
| SCHEMBL8624057 | 0.79 | SELL (0.39) | POLBCYP2C9KDM4EALDH1A1KMT2A | |
| SCHEMBL14468054 | 0.79 | HTT (0.39) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL27981696 | 0.79 | HRH4 (0.35) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL14468053 | 0.79 | GRIN2D (0.31) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL1022548 | 0.72 | GRIN2D (0.47) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL17950545 | 0.72 | PARP1 (0.54) | HSD17B10GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL5702709 | 0.71 | ADORA3 (0.35) | KDM4EKMT2ALMNAGAA | |
| SCHEMBL1019380 | 0.71 | CYP1A2 (0.32) | KMT2A | |
| SCHEMBL107037 | 0.70 | MGAM (0.40) | GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230399312-A1 | SUBSTITUTED PYRIMIDINES AND METHODS OF USE | THERAVANCE BIOPHARMA R&D IP LLC (US) | 2023-12-14 | — | — | US | disclosed |
| WO-2023157722-A1 | POLYMERIZABLE COMPOSITION AND ANTIBACTERIAL MATERIAL | パナソニックＩＰマネジメント株式会社 | 2023-08-24 | — | — | WO | disclosed |
| US-11673879-B2 | Substituted pyrimidines and methods of use | THERAVANCE BIOPHARMA R&D IP, LLC (US) | 2023-06-13 | — | — | US | disclosed |
| WO-2022181492-A1 | POLYMERIZABLE COMPOSITION AND ANTIBACTERIAL MATERIAL | パナソニックＩＰマネジメント株式会社 | 2022-09-01 | — | — | WO | disclosed |
| EP-2121858-B1 | AQUEOUS COATING COMPOSITION HAVING REDUCED PLATE OUT | ARKEMA INC (US) | 2013-10-16 | — | — | EP | disclosed |
| US-8450402-B2 | Method for reducing plate out of aqueous coating compositions | ARKEMA INC. (US) | 2013-05-28 | — | — | US | disclosed |
| US-8450401-B2 | Aqueous coating composition having reduced plate out | ARKEMA INC. (US) | 2013-05-28 | — | — | US | disclosed |
| EP-2121824-B8 | METHOD FOR REDUCING PLATE OUT OF AQUEOUS COATING COMPOSITIONS | ARKEMA INC (US) | 2011-02-23 | — | — | EP | disclosed |
| EP-2121824-B1 | METHOD FOR REDUCING PLATE OUT OF AQUEOUS COATING COMPOSITIONS | ARKEMA INC (US) | 2011-01-12 | — | — | EP | disclosed |
| US-20100324169-A1 | AQUEOUS COATING COMPOSITION HAVING REDUCED PLATE OUT | DOW GLOBAL TECHNOLOGIES, INC (US) | 2010-12-23 | — | — | US | disclosed |
| US-20100319579-A1 | METHOD FOR REDUCING PLATE OUT OF AQUEOUS COATING COMPOSITIONS | ARKEMA INC. | 2010-12-23 | — | — | US | disclosed |
| EP-2121858-A2 | AQUEOUS COATING COMPOSITION HAVING REDUCED PLATE OUT | DOW GLOBAL TECHNOLOGIES INC. (US) | 2009-11-25 | — | — | EP | disclosed |
| EP-2121824-A2 | METHOD FOR REDUCING PLATE OUT OF AQUEOUS COATING COMPOSITIONS | DOW GLOBAL TECHNOLOGIES INC. (US) | 2009-11-25 | — | — | EP | disclosed |
| WO-2008100608-A2 | AQUEOUS COATING COMPOSITION HAVING REDUCED PLATE OUT | DOW GLOBAL TECHNOLOGIES, INC (US) | 2008-08-21 | — | — | WO | disclosed |
| WO-2008100607-A2 | METHOD FOR REDUCING PLATE OUT OF AQUEOUS COATING COMPOSITIONS | DOW GLOBAL TECHNOLOGIES, INC (US) | 2008-08-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11673879-B2 | Substituted pyrimidines and methods of use | ALK, TYMP, ENTPD5 | HSD17B10 3723/4885GRIN2D 3931/4885GRIN3B 2714/4885 |
| US-20230399312-A1 | SUBSTITUTED PYRIMIDINES AND METHODS OF USE | ALK, TYMP, ENTPD5 | HSD17B10 3723/4885GRIN2D 3931/4885GRIN3B 2714/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.