SCHEMBL1019380

SCHEMBL1019380

Cc1cc2[nH]nnc2c(Br)c1C

nearest known ligand 0.32

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.32
MEN1 O00255 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21563201 0.76
SCHEMBL5702709 0.76 ADORA3 (0.35) MEN1KMT2A
SCHEMBL10255309 0.76 EGLN1 (0.34)
SCHEMBL3392523 0.72 POLB (0.34)
SCHEMBL2491037 0.72
SCHEMBL1021702 0.71 HSD17B10 (0.36) KMT2A
SCHEMBL31460305 0.71 MEN1 (0.54) CYP1A2MEN1KMT2A
SCHEMBL8628255 0.71 ADORA3 (0.37) MEN1KMT2A
SCHEMBL1020577 0.69 KMT2A (0.60) CYP1A2MEN1KMT2A
SCHEMBL5458737 0.69 HTR1D (0.37) CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119677749-A Azaquinazoline pan KRAS inhibitors 米拉蒂治疗股份有限公司 2025-03-21 CN disclosed
EP-2121858-B1 AQUEOUS COATING COMPOSITION HAVING REDUCED PLATE OUT ARKEMA INC (US) 2013-10-16 EP disclosed
CN-101617012-B Aqueous coating composition having reduced plate out ARKEMA 2013-08-28 CN disclosed
US-8450401-B2 Aqueous coating composition having reduced plate out ARKEMA INC. (US) 2013-05-28 US disclosed
US-8450402-B2 Method for reducing plate out of aqueous coating compositions ARKEMA INC. (US) 2013-05-28 US disclosed
EP-2121824-B8 METHOD FOR REDUCING PLATE OUT OF AQUEOUS COATING COMPOSITIONS ARKEMA INC (US) 2011-02-23 EP disclosed
EP-2121824-B1 METHOD FOR REDUCING PLATE OUT OF AQUEOUS COATING COMPOSITIONS ARKEMA INC (US) 2011-01-12 EP disclosed
US-20100324169-A1 AQUEOUS COATING COMPOSITION HAVING REDUCED PLATE OUT DOW GLOBAL TECHNOLOGIES, INC (US) 2010-12-23 US disclosed
US-20100319579-A1 METHOD FOR REDUCING PLATE OUT OF AQUEOUS COATING COMPOSITIONS ARKEMA INC. 2010-12-23 US disclosed
CN-101616977-A Be used to reduce the method for the incrustation of water-based paint compositions DOW GLOBAL TECHNOLOGIES INC 2009-12-30 CN disclosed
CN-101617012-A Reduce the water-based paint compositions of incrustation DOW GLOBAL TECHNOLOGIES INC 2009-12-30 CN disclosed
EP-2121858-A2 AQUEOUS COATING COMPOSITION HAVING REDUCED PLATE OUT DOW GLOBAL TECHNOLOGIES INC. (US) 2009-11-25 EP disclosed
EP-2121824-A2 METHOD FOR REDUCING PLATE OUT OF AQUEOUS COATING COMPOSITIONS DOW GLOBAL TECHNOLOGIES INC. (US) 2009-11-25 EP disclosed
WO-2008100608-A2 AQUEOUS COATING COMPOSITION HAVING REDUCED PLATE OUT DOW GLOBAL TECHNOLOGIES, INC (US) 2008-08-21 WO disclosed
WO-2008100607-A2 METHOD FOR REDUCING PLATE OUT OF AQUEOUS COATING COMPOSITIONS DOW GLOBAL TECHNOLOGIES, INC (US) 2008-08-21 WO disclosed
US-4240822-A HERBICIDES AMERICAN CYANAMID COMPANY (US) 1980-12-23 US disclosed