SCHEMBL102177

SCHEMBL102177

COc1c[nH]c(=O)[nH]c1=O

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ATAD2 Q6PL18 1/20 0.52
DPYD Q12882 4/20 0.47
ALDH1A1 P00352 4/20 0.46
SMN1; SMN2 Q16637 2/20 0.46
LMNA P02545 2/20 0.46
GAA P10253 1/20 0.46
MAPT P10636 1/20 0.46
CYP19A1 P11511 1/20 0.46
TSHR P16473 1/20 0.46
THPO P40225 1/20 0.46
MTOR P42345 1/20 0.46
HTT P42858 1/20 0.46
HBB P68871 1/20 0.46
PMP22 Q01453 1/20 0.46
KDM4E B2RXH2 1/20 0.46
HPGD P15428 1/20 0.46
GRIN2D O15399 2/20 0.45
GRIN3B O60391 2/20 0.45
GRIN1 Q05586 2/20 0.45
GRIN2A Q12879 2/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Uracil SCHEMBL28405698 0.86 CRBN (0.57) ATAD2DPYDALDH1A1SMN1; SMN2LMNA
SCHEMBL31090687 0.81 DPYD (0.50) ATAD2DPYDALDH1A1SMN1; SMN2LMNA
SCHEMBL5075425 0.81 SLC22A6 (0.47) ATAD2DPYDALDH1A1SMN1; SMN2LMNA
SCHEMBL1203808 0.78 KMT2A (0.49) ALDH1A1SMN1; SMN2MAPTKDM4EHPGD
SCHEMBL17373188 0.78 ATAD2 (0.45) ATAD2DPYDALDH1A1SMN1; SMN2LMNA
SCHEMBL28777458 0.78 GAA (0.44) ATAD2DPYDALDH1A1SMN1; SMN2LMNA
SCHEMBL6647291 0.77 POLB (0.50) ATAD2DPYDALDH1A1SMN1; SMN2LMNA
SCHEMBL1916526 0.77 ATAD2 (0.47) ATAD2DPYDALDH1A1SMN1; SMN2LMNA
SCHEMBL28419401 0.76 KMT2A (0.37) ATAD2ALDH1A1SMN1; SMN2LMNAGAA
SCHEMBL327290 0.76 DPYD (0.45) ATAD2DPYDALDH1A1SMN1; SMN2LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 24734 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2026106497-A2 FUNCTIONALIZED CIRCULAR RNA AND METHODS AND INTERMEDIATES FOR THEIR PRODUCTION SIEĆ BADAWCZA ŁUKASIEWICZ – PORT POLSKI OSRODEK ROZWOJU TECHNOLOGII (PL) 2026-05-21 WO claimed
CN-122029176-A Containing a plurality of oligonucleotides modified oligonucleotides 阿达尔克斯制药有限公司 2026-05-12 CN claimed
CN-122029177-A Oligonucleotides containing multiple ligands and/or lipids 阿达尔克斯制药有限公司 2026-05-12 CN claimed
CN-122028913-A Oligonucleotides containing ligands in nucleobases, 2 'or 3' positions 阿达尔克斯制药有限公司 2026-05-12 CN claimed
US-12577554-B2 Methods for purification of messenger RNA TRANSLATE BIO, INC. (US) 2026-03-17 US claimed
US-12569572-B2 Messenger RNA therapy for the treatment of Friedreich's ataxia TRANSLATE BIO, INC. (US) 2026-03-10 US claimed
US-12552858-B2 Methods and compositions for delivering mRNA coded antibodies TRANSLATE BIO, INC. (US) 2026-02-17 US claimed
EP-4676446-A1 NOVEL LIPID NANOPARTICLE FORMULATIONS FOR DELIVERY OF NUCLEIC ACIDS CureVac SE (DE) 2026-01-14 EP claimed
US-20260000792-A1 POLYNUCLEOTIDES ENCODING ARGINASE 1 FOR THE TREATMENT OF ARGINASE DEFICIENCY MODERNATX INC (US) 2026-01-01 US claimed
EP-4658664-A1 CAP ANALOGS WITH 5'-TERMINAL ACYCLIC GUANOSINE DERIVATIVE CureVac SE (DE) 2025-12-10 EP claimed
US-6369237-B1 ENZYME INHIBITORS OF DNA GLYCOLASE PRESIDENT AND FELLOWS OF HARVARD COLLEGE 2002-04-09 US claimed
EP-1163374-A2 ARRAYS OF ORGANIC COMPOUNDS ATTACHED TO SURFACES Syntrix Biochip, Inc. (US) 2001-12-19 EP claimed
WO-2001070776-A2 NIMR COMPOSITIONS AND THEIR METHODS OF USE TRUSTEES OF TUFTS COLLEGE (US) 2001-09-27 WO claimed
WO-2000033084-A2 ARRAYS OF ORGANIC COMPOUNDS ATTACHED TO SURFACES SYNTRIX BIOCHIP, INC. (US) 2000-06-08 WO claimed
US-5998596-A Inhibition of protein kinase activity by aptameric action of oligonucleotides THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 1999-12-07 US claimed
WO-1998042723-A9 METHODS AND COMPOSITIONS FOR THE DIAGNOSIS AND TREATMENT OF NEUROPSYCHIATRIC DISORDERS 1999-03-04 WO claimed
WO-1998039334-A9 DNA GLYCOSYLASE INHIBITORS, AND USES RELATED THERETO 1999-02-18 WO claimed
WO-1998039334-A1 DNA GLYCOSYLASE INHIBITORS, AND USES RELATED THERETO PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 1998-09-11 WO claimed
US-5486603-A Oligonucleotide having enhanced binding affinity GILEAD SCIENCES, INC. (US) 1996-01-23 US claimed
US-5118800-A Oligonucleotides possessing a primary amino group in the terminal nucleotide CALIFORNIA INSTITUTE OF TECHNOLOGY (US) 1992-06-02 US claimed