Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.40 |
| ▸ | MMP2 | P08253 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | DPYD | Q12882 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | THPO | P40225 | 1/20 | 0.36 |
| ▸ | MTOR | P42345 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | HBB | P68871 | 1/20 | 0.36 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL102177 | 0.86 | ATAD2 (0.52) | ALDH1A1LMNAATAD2KMT2ADPYD | |
| Uracil SCHEMBL28750821 | 0.78 | — | — | |
| Thymine SCHEMBL574783 | 0.77 | ATAD2 (0.70) | CRBNALDH1A1LMNAATAD2MMP2 | |
| Uracil SCHEMBL5089507 | 0.75 | — | — | |
| Uracil SCHEMBL8235 | 0.75 | — | — | |
| Uracil SCHEMBL11607890 | 0.75 | — | — | |
| Uracil SCHEMBL3798527 | 0.75 | CRBN (1.00) | CRBNALDH1A1LMNAATAD2MMP2 | |
| Fluorouracil SCHEMBL16766745 | 0.74 | ALDH1A1 (0.70) | CRBNALDH1A1LMNAATAD2MMP2 | |
| 5-Bromouracil SCHEMBL27980194 | 0.74 | CRBN (0.63) | CRBNALDH1A1LMNAATAD2MMP2 | |
| Uracil SCHEMBL28426792 | 0.73 | CRBN (0.85) | CRBNALDH1A1LMNAATAD2MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117069785-A | Lipid compounds and lipid nanoparticle compositions | 中生复诺健生物科技(上海)有限公司 | 2023-11-17 | — | — | CN | disclosed |
| CN-111417622-A | Sulfonamides and compositions thereof for the treatment of conditions associated with N L RP activity | 诺华炎症研究公司 | 2020-07-14 | — | — | CN | disclosed |
| CN-111094243-A | Compounds and compositions for treating conditions associated with NLRP activity | 诺华炎症研究公司 | 2020-05-01 | — | — | CN | disclosed |
| CN-111094242-A | Compounds and compositions for treating conditions associated with NLRP activity | 诺华炎症研究公司 | 2020-05-01 | — | — | CN | disclosed |