SCHEMBL2249384

SCHEMBL2249384

c1csc(-c2nc3ccccc3[nH]2)c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 11/20 1.00
KDM4E B2RXH2 10/20 1.00
HPGD P15428 9/20 1.00
NPC1 O15118 8/20 1.00
RAB9A P51151 8/20 1.00
HSD17B10 Q99714 8/20 1.00
SMN1; SMN2 Q16637 6/20 1.00
MAPT P10636 6/20 0.65
MEN1 O00255 4/20 0.65
KMT2A Q03164 4/20 0.65
ALOX15 P16050 3/20 0.65
MAPK1 P28482 3/20 0.65
NPSR1 Q6W5P4 2/20 0.65
TSHR P16473 2/20 0.65
USP2 O75604 1/20 0.65
TP53 P04637 7/20 0.65
GAA P10253 4/20 0.65
GLA P06280 3/20 0.65
TDP1 Q9NUW8 2/20 0.65
LMNA P02545 3/20 0.62

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19176145 0.85 NPC1 (0.74) ALDH1A1KDM4EHPGDNPC1RAB9A
SCHEMBL2248581 0.81 KDM4E (0.69) ALDH1A1KDM4EHPGDNPC1RAB9A
SCHEMBL10376423 0.80 KDM4E (0.67) ALDH1A1KDM4EHPGDNPC1RAB9A
SCHEMBL16332241 0.80 ALDH1A1 (0.67) ALDH1A1KDM4EHPGDNPC1RAB9A
SCHEMBL12543424 0.79 NPC1 (0.80) ALDH1A1KDM4EHPGDNPC1RAB9A
SCHEMBL1391679 0.79 KDM4E (0.78) ALDH1A1KDM4EHPGDNPC1RAB9A
SCHEMBL12082222 0.79 RAB9A (0.69) ALDH1A1KDM4EHPGDNPC1RAB9A
SCHEMBL28601354 0.79 ALDH1A1 (1.00) ALDH1A1KDM4EHPGDNPC1RAB9A
SCHEMBL6420845 0.79 ALDH1A1 (0.65) ALDH1A1KDM4EHPGDNPC1RAB9A
SCHEMBL1544650 0.79 ALDH1A1 (0.65) ALDH1A1KDM4EHPGDNPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 343 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119350726-A High-wear-resistance and high-tearing-resistance tire tread rubber and preparation method thereof 环球石墨烯(青岛)有限公司 2025-01-24 CN claimed
CN-119144220-A High-solid low-viscosity acrylic polyurethane finish paint and preparation method thereof 山东孚日宣威新材料科技有限公司 2024-12-17 CN claimed
CN-118755156-A Controllable cross-linked graphene modified natural rubber with high vulcanization efficiency and low heat generation and water phase synergistic coagulation simple preparation process thereof 中北大学 2024-10-11 CN claimed
CN-118639253-A Alkaline water electrolysis cell sealing gasket and preparation method thereof 远景氢能源科技(江苏)有限公司 2024-09-13 CN claimed
CN-118108982-A Antioxidant based on waste rubber powder and preparation and application thereof in rubber 中国科学院大连化学物理研究所 2024-05-31 CN claimed
CN-118024645-A Efficient preparation process of high-modulus graphene oxide/natural rubber uniformly-cured solid load tire 中北大学 2024-05-14 CN claimed
CN-117986703-A Preparation method of heat-resistant low-pressure-change damping rubber part for automobile 奇瑞汽车股份有限公司 2024-05-07 CN claimed
CN-117757156-A Graphene modified natural rubber with strong interface effect based on free radical annihilation reaction and enhanced and toughened simultaneously 中北大学 2024-03-26 CN claimed
CN-117397903-A Antistatic insole and preparation method thereof 际华三五一五皮革皮鞋有限公司 2024-01-16 CN claimed
CN-113856577-B Magnetic control wave-absorbing capsule and preparation method thereof 国网重庆市电力公司营销服务中心 2023-12-19 CN claimed
CN-111171423-A Rubber treating agent for bonding fluororubber and metal and preparation method thereof 广东东方一哥新材料股份有限公司 2020-05-19 CN claimed
CN-111073373-A Phosphatized epoxy coating and preparation method thereof 袁芬芬 2020-04-28 CN claimed
CN-110845769-A High-damping natural rubber material 安徽微威胶件集团有限公司 2020-02-28 CN claimed
CN-110747644-A Wear-resistant slurry for flame-retardant cotton cloth 沛县新丝路纺织有限公司 2020-02-04 CN claimed
CN-109097759-B A kind of gold and silver coating Anti- tarnishing protective agent and preparation method thereof and application method 深圳市傲新源科技有限公司 2019-07-26 CN claimed
CN-109097759-A A kind of gold and silver coating Anti- tarnishing protective agent and preparation method thereof and application method 深圳市傲新源科技有限公司 2018-12-28 CN claimed
CN-102347107-A Hard EPR (ethylene propylene rubber) insulated power cable for ships and oceans and manufacturing method thereof JIANGSU YUANYANG CABLE CO LTD 2012-02-08 CN claimed
EP-2251010-A1 Use of thiabendazole and derivatives thereof for the therapy of neurological conditions Sygnis Bioscience GmbH & Co. KG (DE) 2010-11-17 EP claimed
WO-2010127878-A2 USE OF THIABENDAZOLE AND DERIVATIVES THEREOF FOR THE THERAPHY OF NEUROLOGICAL CONDITIONS SYGNIS BIOSCIENCE GMBH & CO. KG (DE) 2010-11-11 WO claimed
US-4057425-A SILVER HALIDE EMULSION POLAROID CORPORATION (US) 1977-11-08 US claimed