Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 18/20 | 0.51 |
| ▸ | DPP8 | Q6V1X1 | 13/20 | 0.51 |
| ▸ | DPP9 | Q86TI2 | 13/20 | 0.51 |
| ▸ | FAP | Q12884 | 10/20 | 0.48 |
| ▸ | DPP7 | Q9UHL4 | 9/20 | 0.48 |
| ▸ | GRM8 | O00222 | 1/20 | 0.42 |
| ▸ | GRM6 | O15303 | 1/20 | 0.42 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.42 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.42 |
| ▸ | GSR | P00390 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.42 |
| ▸ | GRM5 | P41594 | 1/20 | 0.42 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.42 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.42 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.42 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.42 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.42 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.42 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12781666 | 0.80 | DPP4 (0.65) | DPP4DPP8DPP9FAPDPP7 | |
| SCHEMBL8353305 | 0.80 | DPP4 (0.65) | DPP4DPP8DPP9FAPDPP7 | |
| SCHEMBL5788741 | 0.74 | ALOX15 (0.42) | DPP4DPP8DPP9FAPDPP7 | |
| SCHEMBL5788998 | 0.74 | ALOX15 (0.42) | DPP4DPP8DPP9FAPDPP7 | |
| SCHEMBL8352775 | 0.73 | DPP4 (0.39) | DPP4DPP8DPP9FAPDPP7 | |
| SCHEMBL21880082 | 0.73 | DPP4 (0.39) | DPP4DPP8DPP9FAPDPP7 | |
| SCHEMBL9509992 | 0.72 | DPP4 (0.57) | DPP4DPP8DPP9FAPDPP7 | |
| SCHEMBL8353687 | 0.72 | DPP4 (0.49) | DPP4DPP8DPP9FAPDPP7 | |
| SCHEMBL13525326 | 0.72 | DPP4 (0.60) | DPP4DPP8DPP9FAPDPP7 | |
| SCHEMBL14364794 | 0.72 | DPP4 (0.40) | DPP4DPP8DPP9FAPDPP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1713780-B1 | NOVEL INHIBITORS OF GLUTAMINYL CYCLASE | PROBIODRUG AG (DE) | 2012-01-18 | — | — | EP | disclosed |