Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 19/20 | 0.49 |
| ▸ | DPP8 | Q6V1X1 | 6/20 | 0.49 |
| ▸ | DPP9 | Q86TI2 | 6/20 | 0.49 |
| ▸ | FAP | Q12884 | 6/20 | 0.48 |
| ▸ | DPP7 | Q9UHL4 | 6/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8353950 | 0.85 | DPP4 (0.44) | DPP4DPP8DPP9FAPDPP7 | |
| SCHEMBL14421482 | 0.84 | DPP4 (0.49) | DPP4DPP8DPP9FAPDPP7 | |
| SCHEMBL5206538 | 0.79 | DPP4 (0.74) | DPP4DPP8DPP9FAPDPP7 | |
| Hydrochloric Acid SCHEMBL1082946 | 0.78 | DPP4 (0.73) | DPP4DPP8DPP9FAPDPP7 | |
| Bromide SCHEMBL5203588 | 0.78 | DPP4 (0.73) | DPP4DPP8DPP9FAPDPP7 | |
| SCHEMBL4110017 | 0.74 | DPP4 (0.50) | DPP4DPP8DPP9FAPDPP7 | |
| SCHEMBL4052407 | 0.72 | DPP4 (0.50) | DPP4DPP8DPP9FAPDPP7 | |
| SCHEMBL3226083 | 0.72 | DPP4 (0.50) | DPP4DPP8DPP9FAPDPP7 | |
| SCHEMBL10219859 | 0.72 | DPP4 (0.51) | DPP4DPP8DPP9FAPDPP7 | |
| SCHEMBL21880082 | 0.71 | DPP4 (0.39) | DPP4DPP8DPP9FAPDPP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003002531-A2 | FLUOROPYRROLIDINES AS DIPEPTIDYL PEPTIDASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2003-01-09 | — | — | WO | disclosed |