Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APOBEC3A | P31941 | 1/20 | 0.50 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.50 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | USP2 | O75604 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | RAD52 | P43351 | 1/20 | 0.43 |
| ▸ | APAF1 | O14727 | 1/20 | 0.43 |
| ▸ | XBP1 | P17861 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10307407 | 0.85 | KMT2A (0.53) | APOBEC3AAPOBEC3GGLAALDH1A1LMNA | |
| SCHEMBL10316134 | 0.83 | GLA (0.47) | GLAALDH1A1LMNAHSP90AA1NPSR1 | |
| Iodide SCHEMBL1789272 | 0.83 | KMT2A (0.52) | APOBEC3AAPOBEC3GGLAALDH1A1LMNA | |
| SCHEMBL677578 | 0.83 | NPSR1 (0.61) | HSP90AA1NPSR1KMT2AATML3MBTL1 | |
| Hydrochloric Acid SCHEMBL28336416 | 0.83 | KMT2A (0.52) | APOBEC3AAPOBEC3GGLAALDH1A1LMNA | |
| SCHEMBL14621511 | 0.81 | APOBEC3A (0.58) | APOBEC3AAPOBEC3GGLAALDH1A1LMNA | |
| SCHEMBL14621506 | 0.80 | APOBEC3A (0.53) | APOBEC3AAPOBEC3GGLAHSP90AA1NPSR1 | |
| SCHEMBL10307403 | 0.80 | ALDH1A1 (0.59) | GLAALDH1A1LMNAHSP90AA1HTT | |
| SCHEMBL10307398 | 0.79 | GLA (0.69) | GLAALDH1A1LMNAHTTSMN1; SMN2 | |
| SCHEMBL16115507 | 0.79 | KMT2A (0.57) | APOBEC3AAPOBEC3GGLAALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8106184-B2 | Nicotinoyl riboside compositions and methods of use | CORNELL UNIVERSITY (US) | 2012-01-31 | — | — | US | disclosed |
| US-20070117765-A1 | Nicotinoyl riboside compositions and methods of use | CORNELL RESEARCH FOUNDATION INC. | 2007-05-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070117765-A1 | Nicotinoyl riboside compositions and methods of use | NNT, CD38, NAMPT | APOBEC3A 1443/4885APOBEC3G 1110/4885GLA 973/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.