Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 4/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | RAD52 | P43351 | 1/20 | 0.42 |
| ▸ | APAF1 | O14727 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | XBP1 | P17861 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | DAO | P14920 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10307407 | 0.98 | KMT2A (0.53) | KMT2AMEN1NPSR1L3MBTL1GLA | |
| Hydrochloric Acid SCHEMBL28336416 | 0.96 | KMT2A (0.52) | KMT2AMEN1NPSR1L3MBTL1GLA | |
| Iodide SCHEMBL5325008 | 0.86 | HSP90AA1 (0.50) | KMT2AMEN1NPSR1L3MBTL1GLA | |
| SCHEMBL10307406 | 0.84 | HSP90AA1 (0.51) | KMT2AMEN1NPSR1L3MBTL1GLA | |
| SCHEMBL10220439 | 0.83 | APOBEC3A (0.50) | KMT2ANPSR1L3MBTL1GLAPABPC1 | |
| Iodide SCHEMBL1789963 | 0.83 | HSP90AA1 (0.58) | KMT2AMEN1NPSR1L3MBTL1GLA | |
| SCHEMBL10316134 | 0.81 | GLA (0.47) | KMT2ANPSR1L3MBTL1GLAPABPC1 | |
| SCHEMBL677578 | 0.81 | NPSR1 (0.61) | KMT2AMEN1NPSR1L3MBTL1ATM | |
| SCHEMBL16115507 | 0.81 | KMT2A (0.57) | KMT2AMEN1NPSR1L3MBTL1GLA | |
| SCHEMBL10307404 | 0.81 | HSP90AA1 (0.59) | KMT2AMEN1NPSR1GLAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8287753-B2 | Gel electrolyte composition, method of fabricating thereof and dye-sensitized solar cell using the same | INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) | 2012-10-16 | — | — | US | disclosed |
| US-20110114167-A1 | GEL ELECTROLYTE COMPOSITION, METHOD OF FABRICATING THEREOF AND DYE-SENSITIZED SOLAR CELL USING THE SAME | INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) | 2011-05-19 | — | — | US | disclosed |