Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP3K5 | Q99683 | 20/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10220572 | 0.88 | MAP3K5 (0.47) | MAP3K5 | |
| SCHEMBL10222463 | 0.79 | MAP3K5 (0.63) | MAP3K5 | |
| SCHEMBL232606 | 0.78 | MAP3K5 (0.55) | MAP3K5 | |
| SCHEMBL10222555 | 0.76 | ALDH1A1 (0.40) | — | |
| SCHEMBL21461157 | 0.75 | MAP3K5 (0.52) | MAP3K5 | |
| SCHEMBL235293 | 0.73 | MAP3K5 (0.52) | MAP3K5 | |
| SCHEMBL28668610 | 0.72 | MAP3K5 (0.53) | MAP3K5 | |
| Hydrochloric Acid SCHEMBL28657089 | 0.72 | MAP3K5 (0.51) | MAP3K5 | |
| SCHEMBL21461103 | 0.72 | MAP3K5 (0.52) | MAP3K5 | |
| SCHEMBL230744 | 0.70 | MAP3K5 (0.57) | MAP3K5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012003387-A1 | APOPTOSIS SIGNAL-REGULATING KINASE INHIBITORS | GILEAD SCIENCES, INC. (US) | 2012-01-05 | — | — | WO | disclosed |