Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 4/20 | 0.69 |
| ▸ | HTT | P42858 | 3/20 | 0.66 |
| ▸ | LMNA | P02545 | 3/20 | 0.66 |
| ▸ | TP53 | P04637 | 2/20 | 0.66 |
| ▸ | PKM | P14618 | 1/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.61 |
| ▸ | TSHR | P16473 | 2/20 | 0.60 |
| ▸ | GAA | P10253 | 1/20 | 0.60 |
| ▸ | TNF | P01375 | 1/20 | 0.58 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20242949 | 0.93 | TLR8 (0.70) | TLR8HTTLMNATP53PKM | |
| SCHEMBL2943250 | 0.93 | TLR8 (0.70) | TLR8HTTLMNATP53PKM | |
| SCHEMBL31066875 | 0.93 | TLR8 (0.70) | TLR8HTTLMNATP53PKM | |
| SCHEMBL17053182 | 0.93 | TLR8 (0.70) | TLR8HTTLMNATP53PKM | |
| SCHEMBL9274775 | 0.93 | TLR8 (0.70) | TLR8HTTLMNATP53PKM | |
| SCHEMBL31066882 | 0.93 | TLR8 (0.70) | TLR8HTTLMNATP53PKM | |
| Hydrochloric Acid SCHEMBL8158771 | 0.92 | TLR8 (0.68) | TLR8HTTLMNATP53PKM | |
| SCHEMBL2330274 | 0.89 | LMNA (0.69) | TLR8HTTLMNATP53PKM | |
| SCHEMBL229041 | 0.89 | POLB (0.67) | HTTLMNATP53PKMSMN1; SMN2 | |
| SCHEMBL10005374 | 0.88 | TLR8 (0.71) | TLR8HTTLMNATP53SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020123670-A1 | SMALL MOLECULE INHIBITORS OF THE ANDROGEN RECEPTOR ACTIVITY AND/OR EXPRESSION AND USES THEREOF | ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (US) | 2020-06-18 | — | — | WO | disclosed |
| EP-2585462-B1 | FUSED HETEROCYCLIC COMPOUNDS AS PHOSPHODIESTERASES (PDES) INHIBITORS | TAKEDA PHARMACEUTICALS CO (JP) | 2020-02-26 | — | — | EP | disclosed |
| US-20160172119-A9 | DYE-SENSITIZED PHOTOELECTRIC CONVERSION ELEMENT | GAKKO HOUJIN TOIN GAKUEN (JP) | 2016-06-16 | — | — | US | disclosed |
| US-20150129035-A1 | DYE-SENSITIZED PHOTOELECTRIC CONVERSION ELEMENT | GAKKO HOUJIN TOIN GAKUEN (JP) | 2015-05-14 | — | — | US | disclosed |
| US-8461180-B2 | Inhibitors of human immunodeficiency virus replication | GILEAD SCIENCES, INC. (US) | 2013-06-11 | — | — | US | disclosed |
| US-20110041915-A1 | DYE-SENSITIZED PHOTOELECTRIC CONVERSION ELEMENT | PECCELL TECHNOLOGIES, INC. (JP) | 2011-02-24 | — | — | US | disclosed |
| EP-2276103-A1 | DYE-SENSITIZED PHOTOELECTRIC CONVERSION ELEMENT | Peccell Technologies Inc (JP) | 2011-01-19 | — | — | EP | disclosed |
| WO-2009062308-A1 | INHIBITORS OF HUMAN IMMUNODEFICIENCY VIRUS REPLICATION | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2009-05-22 | — | — | WO | disclosed |
| EP-0267136-B1 | QUATERNARY AMMONIUM SALTS USED AS PHASE TRANSFER CATALYSTS | ALTER, S.A. (ES) | 1990-09-19 | — | — | EP | disclosed |
| US-4880894-A | Quaternary ammonium salts used as phase transfer catalyst | ALTER, S.A. (ES) | 1989-11-14 | — | — | US | disclosed |
| EP-0267136-A2 | Quaternary ammonium salts used as phase transfer catalysts | ALTER, S.A. (ES) | 1988-05-11 | — | — | EP | disclosed |