SCHEMBL10226002

SCHEMBL10226002

c1ccc(-c2ccc3oc4c(-c5ccc6[nH]c7ccc(-c8cc(-c9ccccc9)cc9c8oc8ccc(-c%10ccccc%10)cc89)cc7c6c5)cc(-c5ccccc5)cc4c3c2)cc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 2/20 0.42
KDM4E B2RXH2 1/20 0.42
MEN1 O00255 1/20 0.42
MAPT P10636 1/20 0.42
KMT2A Q03164 1/20 0.42
PIM1 P11309 1/20 0.42
CSNK2A2 P19784 1/20 0.42
CSNK2B P67870 1/20 0.42
PIM3 Q86V86 1/20 0.42
PIM2 Q9P1W9 1/20 0.42
CDK4 P11802 2/20 0.40
CCND1 P24385 2/20 0.40
PLA2G2A P14555 3/20 0.39
PLA2G4A P47712 3/20 0.39
JAK2 O60674 1/20 0.37
GABRA1 P14867 2/20 0.36
GABRG2 P18507 2/20 0.36
GABRB3 P28472 2/20 0.36
GABRA5 P31644 2/20 0.36
GABRA3 P34903 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10227111 1.00 GAA (0.42) GAAKDM4EMEN1MAPTKMT2A
SCHEMBL10226004 0.97 PIM1 (0.41) GAAKDM4EMEN1MAPTKMT2A
SCHEMBL10226451 0.96 PIM1 (0.40) GAAKDM4EMEN1MAPTKMT2A
SCHEMBL10226454 0.96 PIM1 (0.40) GAAKDM4EMEN1MAPTKMT2A
SCHEMBL10226455 0.94 PLA2G2A (0.39) GAAKDM4EMEN1MAPTKMT2A
SCHEMBL10226935 0.90 PIM1 (0.39) GAAKDM4EMEN1MAPTKMT2A
SCHEMBL788523 0.90 KDM4E (0.44) GAAKDM4EMEN1MAPTKMT2A
SCHEMBL10227407 0.90 KDM4E (0.42) GAAKDM4EMEN1MAPTKMT2A
SCHEMBL18080840 0.89 LIMK1 (0.37) GAAKDM4EMEN1MAPTKMT2A
SCHEMBL10226459 0.88 CDK4 (0.40) GAAKDM4EMEN1MAPTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9450188-B2 Carbazole derivative, light-emitting element material and organic semiconductor material SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2016-09-20 US disclosed
US-20140145175-A1 Carbazole Derivative, Light-Emitting Element Material and Organic Semiconductor Material SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2014-05-29 US disclosed
US-8642782-B2 Carbazole derivative, light-emitting element material and organic semiconductor material SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2014-02-04 US disclosed
US-20120071668-A1 Carbazole Derivative, Light-Emitting Element Material and Organic Semiconductor Material SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2012-03-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120071668-A1 Carbazole Derivative, Light-Emitting Element Material and Organic Semiconductor Material SLC39A3, SULT1A1, NUTF2 GAA 3827/4885KDM4E 3917/4885MEN1 3326/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.