SCHEMBL1022604

SCHEMBL1022604

CCCc1ccc(O)c(CC)c1

nearest known ligand 0.72

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BACE1 P56817 1/20 0.72
CNR1 P21554 1/20 0.64
CNR2 P34972 1/20 0.64
ALOX5 P09917 2/20 0.59
ESR1 P03372 3/20 0.52
ESR2 Q92731 3/20 0.52
IAPP P10997 3/20 0.49
MCL1 Q07820 1/20 0.49
HSD17B1 P14061 1/20 0.49
TRPA1 O75762 1/20 0.48
GABRA1 P14867 2/20 0.46
GABRB2 P47870 2/20 0.46
CYP3A4 P08684 1/20 0.46
CYP2D6 P10635 1/20 0.46
DRD2 P14416 1/20 0.46
TSHR P16473 1/20 0.46
NFKB1 P19838 1/20 0.46
DRD1 P21728 1/20 0.46
DRD4 P21917 1/20 0.46
DRD5 P21918 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1021086 0.89 ALOX5 (0.71) BACE1CNR1CNR2ALOX5IAPP
SCHEMBL1023618 0.88 BACE1 (0.68) BACE1CNR1CNR2ALOX5ESR1
SCHEMBL5595846 0.88 BACE1 (0.72) BACE1CNR1CNR2ALOX5ESR1
SCHEMBL51035 0.88 CNR1 (0.64) BACE1CNR1CNR2ALOX5IAPP
SCHEMBL1024796 0.86 BACE1 (0.66) BACE1ESR1ESR2IAPPCYP3A4
SCHEMBL9913999 0.86 CNR1 (0.58) BACE1CNR1CNR2ALOX5IAPP
SCHEMBL13966467 0.86 CNR1 (0.62) BACE1CNR1CNR2ALOX5IAPP
SCHEMBL11328457 0.86 BACE1 (0.70) BACE1ESR1ESR2HSD17B1
SCHEMBL1023719 0.85 KAT8 (0.64) BACE1ESR1ESR2CYP3A4HIF1A
SCHEMBL9650041 0.85 KAT8 (0.64) BACE1ESR1ESR2CYP3A4HIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 879 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114276530-A Intermittent phosgene interface method preparation process of polycarbonate and application thereof 深圳市德力塑化工科技有限公司 2022-04-05 CN claimed
CN-103249758-A Isosorbide-containing polycarbonates and their preparation SABIC INNOVATIVE PLASTICS IP 2013-08-14 CN claimed
CN-1938379-B Impact-modified compositions and methods GEN ELECTRIC 2012-05-16 CN claimed
CN-1976995-B Polyarylate compositions GEN ELECTRIC 2010-06-09 CN claimed
CN-100572349-C Method for purifying 1, 1-bis (4 '-hydroxy-3' -methylphenyl) cyclohexane and method for producing polycarbonate therefrom GEN ELECTRIC (NL) 2009-12-23 CN claimed
CN-100554332-C The goods that polycarbonate molding compositions and specious degree thereof improve GEN ELECTRIC (NL) 2009-10-28 CN claimed
CN-100535029-C Method for producing copolyestercarbonates GEN ELECTRIC (NL) 2009-09-02 CN claimed
CN-101374908-A Foamed and foamable high glass transition temperature polymers GEN ELECTRIC (US) 2009-02-25 CN claimed
CN-101370872-A Food service articles of manufacture comprising high temperature polymers GEN ELECTRIC (US) 2009-02-18 CN claimed
CN-101370873-A Annular or tubular shaped articles of novel polymer blends GEN ELECTRIC (US) 2009-02-18 CN claimed
CN-1714114-A Polycarbonate copolymers and methods for producing the polycarbonate copolymers GEN ELECTRIC (US) 2005-12-28 CN claimed
CN-1688650-A Flame retardant resinous compositions and method GEN ELECTRIC (US) 2005-10-26 CN claimed
CN-1656141-A Method for copolyestercarbonate synthesis GEN ELECTRIC (US) 2005-08-17 CN claimed
CN-1541239-A Melt Polycarbonate Catalyst System ͨ�õ�����˾ 2004-10-27 CN claimed
CN-1500105-A Melt polycarbonate catalyst systems ͨ�õ�����˾ 2004-05-26 CN claimed
CN-1492897-A Melt polycarbonate catalyst system ͨ�õ�����˾ 2004-04-28 CN claimed
EP-1360221-A1 MELT POLYCARBONATE CATALYST SYSTEMS GENERAL ELECTRIC COMPANY (US) 2003-11-12 EP claimed
EP-1358247-A2 MELT POLYCARBONATE CATALYST SYSTEMS GENERAL ELECTRIC COMPANY (US) 2003-11-05 EP claimed
WO-2002055585-A2 MELT POLYCARBONATE CATALYST SYSTEMS GEN ELECTRIC (US) 2002-07-18 WO claimed
WO-2002055584-A1 MELT POLYCARBONATE CATALYST SYSTEMS GENERAL ELECTRIC COMPANY (US) 2002-07-18 WO claimed