Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | EZH2 | Q15910 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | APEX1 | P27695 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | RBP4 | P02753 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1026429 | 0.94 | TSHR (0.53) | TSHREZH2TDP1APEX1MAPK1 | |
| SCHEMBL1023565 | 0.88 | TSHR (0.46) | TSHRTDP1MAPK1HTT | |
| SCHEMBL2923735 | 0.88 | TSHR (0.46) | TSHREZH2TDP1HTT | |
| SCHEMBL2930878 | 0.84 | TSHR (0.49) | TSHREZH2TDP1HTT | |
| SCHEMBL1022837 | 0.83 | TSHR (0.49) | TSHREZH2TDP1HTT | |
| SCHEMBL1023784 | 0.83 | TSHR (0.36) | TSHRAPEX1MAPK1 | |
| SCHEMBL1023766 | 0.82 | TSHR (0.50) | TSHRTDP1MAPK1HTT | |
| SCHEMBL25176593 | 0.80 | TSHR (0.54) | TSHREZH2TDP1HTT | |
| SCHEMBL15482425 | 0.80 | TSHR (0.51) | TSHREZH2TDP1HTT | |
| SCHEMBL6526426 | 0.79 | TSHR (0.55) | TSHREZH2TDP1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8053595-B2 | Process for producing isocyanates | ASAHI KASEI CHEMICALS CORPORATION (JP) | 2011-11-08 | — | — | US | disclosed |
| EP-2088137-B1 | A PROCESS FOR PRODUCING ISOCYANATES | ASAHI KASEI CHEMICALS CORP (JP) | 2011-01-12 | — | — | EP | disclosed |
| US-20100029981-A1 | PROCESS FOR PRODUCING ISOCYANATES | ASAHI KASEI CHEMICALS CORPORATION (JP) | 2010-02-04 | — | — | US | disclosed |
| EP-2088137-A1 | METHOD FOR PRODUCING ISOCYANATE | Asahi Kasei Chemicals Corporation (JP) | 2009-08-12 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100029981-A1 | PROCESS FOR PRODUCING ISOCYANATES | PAH, ALKBH3, GRHPR | TSHR 4077/4885EZH2 3906/4885TDP1 3597/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.