Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | APEX1 | P27695 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1023566 | 0.88 | MEN1 (0.39) | TSHRMAPK1ALDH1A1 | |
| SCHEMBL2923737 | 0.87 | TSHR (0.34) | TSHR | |
| SCHEMBL1026429 | 0.85 | TSHR (0.53) | TSHRAPEX1NPC1RAB9AMAPK1 | |
| SCHEMBL1022938 | 0.83 | TSHR (0.48) | TSHRAPEX1MAPK1 | |
| SCHEMBL2930879 | 0.83 | KCNA3 (0.37) | TSHR | |
| SCHEMBL15482426 | 0.79 | TSHR (0.38) | TSHRNPC1RAB9AALDH1A1 | |
| SCHEMBL15482398 | 0.78 | MDH1 (0.40) | TSHR | |
| SCHEMBL2928596 | 0.77 | TSHR (0.40) | TSHRNPC1 | |
| SCHEMBL2930738 | 0.75 | TSHR (0.38) | TSHR | |
| SCHEMBL2934223 | 0.75 | TSHR (0.41) | TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8053595-B2 | Process for producing isocyanates | ASAHI KASEI CHEMICALS CORPORATION (JP) | 2011-11-08 | — | — | US | disclosed |
| EP-2088137-B1 | A PROCESS FOR PRODUCING ISOCYANATES | ASAHI KASEI CHEMICALS CORP (JP) | 2011-01-12 | — | — | EP | disclosed |
| US-20100029981-A1 | PROCESS FOR PRODUCING ISOCYANATES | ASAHI KASEI CHEMICALS CORPORATION (JP) | 2010-02-04 | — | — | US | disclosed |
| EP-2088137-A1 | METHOD FOR PRODUCING ISOCYANATE | Asahi Kasei Chemicals Corporation (JP) | 2009-08-12 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100029981-A1 | PROCESS FOR PRODUCING ISOCYANATES | PAH, ALKBH3, GRHPR | TSHR 4077/4885APEX1 1998/4885NPC1 3442/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.