Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | PLAU | P00749 | 1/20 | 0.42 |
| ▸ | PTPRC | P08575 | 1/20 | 0.42 |
| ▸ | S100A4 | P26447 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10230495 | 1.00 | CYP1A2 (0.54) | CYP1A2ALDH1A1TSHRGPR35HSD17B10 | |
| SCHEMBL3697952 | 0.85 | CYP1A2 (0.59) | CYP1A2ALDH1A1TSHRGPR35HSD17B10 | |
| SCHEMBL8521008 | 0.83 | CYP1A2 (0.58) | CYP1A2ALDH1A1TSHRGPR35HSD17B10 | |
| SCHEMBL28248090 | 0.83 | CYP1A2 (0.53) | CYP1A2ALDH1A1TSHRGPR35HSD17B10 | |
| SCHEMBL31014201 | 0.83 | CYP1A2 (0.58) | CYP1A2ALDH1A1TSHRGPR35HSD17B10 | |
| SCHEMBL506668 | 0.83 | CYP1A2 (0.58) | CYP1A2ALDH1A1TSHRGPR35HSD17B10 | |
| SCHEMBL5281897 | 0.80 | CYP1A2 (0.64) | CYP1A2ALDH1A1TSHRGPR35HSD17B10 | |
| SCHEMBL8125004 | 0.80 | ALDH1A1 (0.53) | CYP1A2ALDH1A1TSHRGPR35HSD17B10 | |
| SCHEMBL14436535 | 0.80 | CYP1A2 (0.54) | CYP1A2ALDH1A1TSHRGPR35HSD17B10 | |
| SCHEMBL6256628 | 0.80 | ALDH1A1 (0.57) | CYP1A2ALDH1A1TSHRGPR35HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102443030-B | The Nucleotide of the labeled nucleotide that light can rupture and nucleosides and mark and nucleosides and its using method in DNA sequencing | LASERGEN INC. (US) | 2015-12-16 | — | — | CN | disclosed |
| US-8148503-B2 | Nucleotides and nucleosides and methods for their use in DNA sequencing | LASERGEN, INC. (US) | 2012-04-03 | — | — | US | disclosed |
| US-20100041041-A1 | NUCLEOTIDES AND NUCLEOSIDES AND METHODS FOR THEIR USE IN DNA SEQUENCING | AGILENT TECHNOLOGIES, INC. | 2010-02-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100041041-A1 | NUCLEOTIDES AND NUCLEOSIDES AND METHODS FOR THEIR USE IN DNA SEQUENCING | UNG, NT5C2, NT5E | CYP1A2 1691/4885ALDH1A1 1889/4885TSHR 4231/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.