SCHEMBL31014201

SCHEMBL31014201

O=[N+]([O-])c1ccccc1C(O)O

nearest known ligand 0.58

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 2/20 0.58
ALDH1A1 P00352 6/20 0.56
TSHR P16473 2/20 0.54
GPR35 Q9HC97 2/20 0.50
HSD17B10 Q99714 1/20 0.48
TDP1 Q9NUW8 4/20 0.46
MEN1 O00255 2/20 0.45
KMT2A Q03164 2/20 0.45
PLAU P00749 1/20 0.44
PTPRC P08575 1/20 0.44
S100A4 P26447 1/20 0.44
CA1 P00915 1/20 0.43
CA2 P00918 1/20 0.43
MMP1 P03956 1/20 0.43
MMP2 P08253 1/20 0.43
MMP9 P14780 1/20 0.43
MMP8 P22894 1/20 0.43
MMP13 P45452 1/20 0.43
CTSD P07339 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8521008 1.00 CYP1A2 (0.58) CYP1A2ALDH1A1TSHRGPR35HSD17B10
SCHEMBL3697952 0.89 CYP1A2 (0.59) CYP1A2ALDH1A1TSHRGPR35HSD17B10
SCHEMBL506668 0.87 CYP1A2 (0.58) CYP1A2ALDH1A1TSHRGPR35HSD17B10
SCHEMBL888202 0.83 ALDH1A1 (0.57) CYP1A2ALDH1A1TSHRGPR35HSD17B10
SCHEMBL5281897 0.83 CYP1A2 (0.64) CYP1A2ALDH1A1TSHRGPR35HSD17B10
SCHEMBL10230494 0.83 CYP1A2 (0.54) CYP1A2ALDH1A1TSHRGPR35HSD17B10
SCHEMBL6256628 0.83 ALDH1A1 (0.57) CYP1A2ALDH1A1TSHRGPR35HSD17B10
SCHEMBL12232403 0.83 CYP1A2 (0.54) CYP1A2ALDH1A1TSHRGPR35HSD17B10
SCHEMBL14436535 0.83 CYP1A2 (0.54) CYP1A2ALDH1A1TSHRGPR35HSD17B10
SCHEMBL31146698 0.83 ALDH1A1 (0.57) CYP1A2ALDH1A1TSHRGPR35HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118440025-B Zhu Gongjun acid derivative and preparation method and application thereof 济南爱思医药科技有限公司 2024-09-17 CN disclosed
CN-118440025-A Zhu Gongjun acid derivative and preparation method and application thereof 济南爱思医药科技有限公司 2024-08-06 CN disclosed