Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 13/20 | 0.68 |
| ▸ | KDM4E | B2RXH2 | 12/20 | 0.68 |
| ▸ | HSD17B10 | Q99714 | 8/20 | 0.68 |
| ▸ | HPGD | P15428 | 7/20 | 0.68 |
| ▸ | GAA | P10253 | 8/20 | 0.58 |
| ▸ | GLA | P06280 | 7/20 | 0.58 |
| ▸ | CA2 | P00918 | 1/20 | 0.57 |
| ▸ | STS | P08842 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.55 |
| ▸ | ALDH2 | P05091 | 2/20 | 0.55 |
| ▸ | NPC1 | O15118 | 2/20 | 0.55 |
| ▸ | CASP3 | P42574 | 2/20 | 0.55 |
| ▸ | RAB9A | P51151 | 2/20 | 0.55 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.55 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.55 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20703812 | 0.93 | ALDH1A1 (0.69) | ALDH1A1KDM4EHSD17B10HPGDGAA | |
| SCHEMBL6679222 | 0.87 | ALDH1A1 (0.62) | ALDH1A1KDM4EHSD17B10HPGDGAA | |
| SCHEMBL20832199 | 0.86 | ALDH1A1 (0.65) | ALDH1A1KDM4EHSD17B10HPGDGAA | |
| SCHEMBL20710799 | 0.85 | ALDH1A1 (0.59) | ALDH1A1KDM4EHSD17B10HPGDGAA | |
| SCHEMBL29374108 | 0.85 | ALDH1A1 (0.59) | ALDH1A1KDM4EHSD17B10HPGDGAA | |
| SCHEMBL140039 | 0.84 | ALDH1A1 (0.66) | ALDH1A1KDM4EHSD17B10HPGDGAA | |
| SCHEMBL380623 | 0.84 | ALDH1A1 (0.66) | ALDH1A1KDM4EHSD17B10HPGDGAA | |
| SCHEMBL29391759 | 0.84 | ALDH1A1 (0.66) | ALDH1A1KDM4EHSD17B10HPGDGAA | |
| SCHEMBL4610846 | 0.84 | ALDH1A1 (0.66) | ALDH1A1KDM4EHSD17B10HPGDGAA | |
| SCHEMBL7058731 | 0.84 | ALDH1A1 (0.66) | ALDH1A1KDM4EHSD17B10HPGDGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8557547-B2 | Phosphotriesterase from agrobacterium radiobacter P230 | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) | 2013-10-15 | — | — | US | disclosed |
| US-8557547-B2 | Phosphotriesterase from agrobacterium radiobacter P230 | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) | 2013-10-15 | — | — | US | disclosed |
| US-8557547-B2 | Phosphotriesterase from agrobacterium radiobacter P230 | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) | 2013-10-15 | — | — | US | disclosed |
| US-20130040367-A1 | PHOSPHOTRIESTERASE FROM AGROBACTERIUM RADIOBACTER P230 | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) | 2013-02-14 | — | — | US | disclosed |
| US-20130040367-A1 | PHOSPHOTRIESTERASE FROM AGROBACTERIUM RADIOBACTER P230 | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) | 2013-02-14 | — | — | US | disclosed |
| US-8293244-B2 | for use in pesticide bioremediation strategies; biosensors; genetic engineering; solid phase synthesis | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) | 2012-10-23 | — | — | US | disclosed |
| US-8293244-B2 | for use in pesticide bioremediation strategies; biosensors; genetic engineering; solid phase synthesis | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) | 2012-10-23 | — | — | US | disclosed |
| US-8293244-B2 | for use in pesticide bioremediation strategies; biosensors; genetic engineering; solid phase synthesis | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) | 2012-10-23 | — | — | US | disclosed |
| EP-1392825-B1 | PHOSPHOTRIESTERASE FROM AGROBACTERIUM RADIOBACTER P230 | COMMW SCIENT IND RES ORG (AU) | 2011-01-12 | — | — | EP | disclosed |
| EP-1392825-A4 | PHOSPHOTRIESTERASE FROM AGROBACTERIUM RADIOBACTER P230 | COMMW SCIENT IND RES ORG (AU) | 2005-01-26 | — | — | EP | disclosed |
| US-20040161818-A1 | Phosphotriesterase from agrobacterium radiobacter p230 | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) | 2004-08-19 | — | — | US | disclosed |
| EP-1392825-A1 | PHOSPHOTRIESTERASE FROM AGROBACTERIUM RADIOBACTER P230 | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) | 2004-03-03 | — | — | EP | disclosed |
| WO-2002092803-A1 | PHOSPHOTRIESTERASE FROM AGROBACTERIUM RADIOBACTER P230 | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) | 2002-11-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040161818-A1 | Phosphotriesterase from agrobacterium radiobacter p230 | PPA1, PHPT1, DPY30 | ALDH1A1 1959/4885KDM4E 841/4885HSD17B10 754/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.