Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 known ✓ | P00918 | 1/20 | 0.58 |
| ▸ | CA12 known ✓ | O43570 | 2/20 | 0.53 |
| ▸ | CA1 known ✓ | P00915 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 12/20 | 0.66 |
| ▸ | KDM4E | B2RXH2 | 11/20 | 0.66 |
| ▸ | HSD17B10 | Q99714 | 7/20 | 0.66 |
| ▸ | HPGD | P15428 | 6/20 | 0.66 |
| ▸ | GAA | P10253 | 8/20 | 0.59 |
| ▸ | GLA | P06280 | 7/20 | 0.59 |
| ▸ | STS | P08842 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | ALDH2 | P05091 | 2/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.54 |
| ▸ | MAOB | P27338 | 3/20 | 0.54 |
| ▸ | NPC1 | O15118 | 2/20 | 0.54 |
| ▸ | CASP3 | P42574 | 2/20 | 0.54 |
| ▸ | RAB9A | P51151 | 2/20 | 0.54 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Silver SCHEMBL7614148 | 0.99 | ALDH1A1 (0.64) | ALDH1A1KDM4EHSD17B10HPGDGAA | |
| Lithium Ion SCHEMBL1871467 | 0.99 | ALDH1A1 (0.64) | ALDH1A1KDM4EHSD17B10HPGDGAA | |
| SCHEMBL4610784 | 0.93 | ALDH1A1 (0.64) | ALDH1A1KDM4EHSD17B10HPGDGAA | |
| SCHEMBL20703812 | 0.88 | ALDH1A1 (0.69) | ALDH1A1KDM4EHSD17B10HPGDGAA | |
| SCHEMBL140039 | 0.85 | ALDH1A1 (0.66) | ALDH1A1KDM4EHSD17B10HPGDGAA | |
| SCHEMBL4610846 | 0.85 | ALDH1A1 (0.66) | ALDH1A1KDM4EHSD17B10HPGDGAA | |
| SCHEMBL29391759 | 0.85 | ALDH1A1 (0.66) | ALDH1A1KDM4EHSD17B10HPGDGAA | |
| SCHEMBL7058731 | 0.85 | ALDH1A1 (0.66) | ALDH1A1KDM4EHSD17B10HPGDGAA | |
| Phosphoric Acid SCHEMBL9224251 | 0.84 | ALDH1A1 (0.64) | ALDH1A1KDM4EHSD17B10HPGDGAA | |
| SCHEMBL1023154 | 0.84 | ALDH1A1 (0.68) | ALDH1A1KDM4EHSD17B10HPGDGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 136 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4351604-A1 | ENGINEERED MICROORGANISMS FOR DETECTION OF DISEASED CELLS | Microbial Machines, Inc. (US) | 2024-04-17 | — | — | EP | claimed |
| US-20240118283-A1 | ENGINEERED MICROORGANISMS FOR DETECTION OF DISEASED CELLS | MICROBIAL MACHINES, INC. | 2024-04-11 | — | — | US | claimed |
| CN-117836432-A | Engineered microorganisms for detection of diseased cells | 微生物机器公司 | 2024-04-05 | — | — | CN | claimed |
| CN-116683025-A | Positive electrode sodium supplement additive and sodium ion battery | 天津中电新能源研究院有限公司 | 2023-09-01 | — | — | CN | claimed |
| WO-2022261290-A1 | ENGINEERED MICROORGANISMS FOR DETECTION OF DISEASED CELLS | MICROBIAL MACHINES, INC. (US) | 2022-12-15 | — | — | WO | claimed |
| CN-110361440-B | Portable electrophoresis titration detection method for activity of alkaline phosphatase | 上海交通大学 | 2021-08-06 | — | — | CN | claimed |
| CN-111225983-A | Method for performing cell culture | 默克专利股份公司 | 2020-06-02 | — | — | CN | claimed |
| US-9090929-B2 | Medium for detecting and differentiating vancomycin-resistant enterococci | OXOID LIMITED (GB) | 2015-07-28 | — | — | US | claimed |
| EP-2186906-B1 | Medium for detecting and differentiating vancomycin-resistant enterococci | OXOID LTD (GB) | 2012-07-25 | — | — | EP | claimed |
| EP-2186906-A2 | Medium for detecting and differentiating vancomycin-resistant enterococci | OXOID LIMITED (GB) | 2010-05-19 | — | — | EP | claimed |
| US-20100120086-A1 | MEDIUM FOR DETECTING AND DIFFERENTIATING VANCOMYCIN-RESISTANT ENTEROCOCCI | OXOID LTD. (GB) | 2010-05-13 | — | — | US | claimed |
| US-20080261264-A1 | Culture Medium for Detecting of Clostridium Perfringens | UNIVERSIDADE DE SANTIAGO DE COMPOSTELA (ES) | 2008-10-23 | — | — | US | claimed |
| EP-1816209-A2 | CULTURE MEDIUM FOR THE DETECTION OF CLOSTRIDIUM PERFRINGENS | UNIVERSIDADE DE SANTIAGO DE COMPOSTELA (ES) | 2007-08-08 | — | — | EP | claimed |
| US-12629457-B2 | Structural implant for bone repair | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2026-05-19 | — | — | US | disclosed |
| US-20260048174-A1 | DEVICES AND METHODS FOR AMELIORATING IMPLANT-INDUCED INFLAMMATION | CERAPEDICS INC (US) | 2026-02-19 | — | — | US | disclosed |
| US-20260036584-A1 | COMPOSITIONS AND METHODS TO DETECT GASTROINTESTINAL DISEASE | THE BOARD OF SUPERVISORS OF LOUISIANA STATE UNIV AND AGRICULTURAL AND MECHANICAL COLLEGE (US) | 2026-02-05 | — | — | US | disclosed |
| WO-1993020054-A1 | EUROPIUM AND TERBIUM CHELATORS FOR TIME-RESOLVED FLUOROMETRIC ASSAYS | NORDION INTERNATIONAL INC. (CA) | 1993-10-14 | — | — | WO | disclosed |
| US-5179008-A | Hybridoma and monoclonal antibody to FHAP | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 1993-01-12 | — | — | US | disclosed |
| US-5001052-A | Immunoassay for FHAP and antibody useful therewith | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 1991-03-19 | — | — | US | disclosed |
| EP-0359138-A2 | Stabilization and reduction of background fluorescence of hydroxy coumarin ester enzyme substrates | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1990-03-21 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260036584-A1 | COMPOSITIONS AND METHODS TO DETECT GASTROINTESTINAL DISEASE | SI, FABP2, VIP | CA2 2046/4885CA12 364/4885CA1 1332/4885 |
| US-20260048174-A1 | DEVICES AND METHODS FOR AMELIORATING IMPLANT-INDUCED INFLAMMATION | IL15, IL15RA, CMKLR1 | CA2 3016/4885CA12 2695/4885CA1 3167/4885 |
| US-12629457-B2 | Structural implant for bone repair | SOST, BMP2, CAPG | CA2 21/4885CA12 67/4885CA1 26/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.