Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | CNR1 | P21554 | 2/20 | 0.40 |
| ▸ | CES2 | O00748 | 1/20 | 0.40 |
| ▸ | BCHE | P06276 | 1/20 | 0.40 |
| ▸ | CES1 | P23141 | 1/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | CASP7 | P55210 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL87415 | 0.79 | ELANE (0.44) | TDP1KCNH2ALDH1A1HSD17B10TSHR | |
| Pyrene SCHEMBL28193182 | 0.75 | ALDH1A1 (0.61) | TDP1KCNH2ALDH1A1HSD17B10TSHR | |
| SCHEMBL1193690 | 0.75 | KCNH2 (0.50) | KCNH2MCL1TLR8 | |
| Pyrene SCHEMBL8821795 | 0.73 | ALDH1A1 (0.58) | TDP1KCNH2ALDH1A1HSD17B10TSHR | |
| Pyrene SCHEMBL28128984 | 0.73 | ALDH1A1 (0.58) | TDP1KCNH2ALDH1A1HSD17B10TSHR | |
| SCHEMBL18095059 | 0.73 | TDP1 (0.45) | TDP1KCNH2ALDH1A1HSD17B10TSHR | |
| SCHEMBL3421066 | 0.73 | TDP1 (0.45) | TDP1KCNH2ALDH1A1HSD17B10TSHR | |
| SCHEMBL1024206 | 0.73 | PTPN1 (0.50) | TDP1KCNH2ALDH1A1MAPK1CYP1B1 | |
| SCHEMBL2138799 | 0.72 | GCGR (0.47) | TDP1KCNH2ALDH1A1HSD17B10TSHR | |
| SCHEMBL2963335 | 0.72 | PTPN1 (0.41) | TDP1KCNH2ALDH1A1HSD17B10MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1739485-B1 | RESIST COMPOSITION | MITSUBISHI GAS CHEMICAL CO (JP) | 2016-08-31 | — | — | EP | disclosed |
| US-7871751-B2 | Resist composition | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2011-01-18 | — | — | US | disclosed |
| US-20080153031-A1 | Resist composition | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2008-06-26 | — | — | US | disclosed |
| EP-1739485-A1 | RESIST COMPOSITION | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2007-01-03 | — | — | EP | disclosed |