Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 6/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | CASP1 | P29466 | 2/20 | 0.38 |
| ▸ | MPI | P34949 | 1/20 | 0.38 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.38 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | CES2 | O00748 | 1/20 | 0.38 |
| ▸ | BCHE | P06276 | 1/20 | 0.38 |
| ▸ | CES1 | P23141 | 1/20 | 0.38 |
| ▸ | BCL2 | P10415 | 4/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18095059 | 1.00 | TDP1 (0.45) | TDP1CYP1B1ALDH1A1TSHRMAPK1 | |
| SCHEMBL1023271 | 0.73 | TDP1 (0.47) | TDP1CYP1B1ALDH1A1TSHRMAPK1 | |
| Pyrene SCHEMBL28193182 | 0.73 | ALDH1A1 (0.61) | TDP1CYP1B1ALDH1A1TSHRHSD17B10 | |
| Pyrene SCHEMBL8821795 | 0.71 | ALDH1A1 (0.58) | TDP1CYP1B1ALDH1A1TSHRMAPK1 | |
| Pyrene SCHEMBL28128984 | 0.71 | ALDH1A1 (0.58) | TDP1CYP1B1ALDH1A1TSHRMAPK1 | |
| SCHEMBL16601690 | 0.70 | ALDH1A1 (0.47) | TDP1ALDH1A1MAPK1HSD17B10ATM | |
| SCHEMBL87415 | 0.69 | ELANE (0.44) | TDP1CYP1B1ALDH1A1TSHRMAPK1 | |
| Hexane SCHEMBL27665073 | 0.69 | ALDH1A1 (0.50) | TDP1CYP1B1ALDH1A1TSHRMAPK1 | |
| SCHEMBL4562954 | 0.68 | C3AR1 (0.53) | ALDH1A1TSHRMAPK1L3MBTL1KDM4E | |
| SCHEMBL4562956 | 0.68 | C3AR1 (0.53) | ALDH1A1TSHRMAPK1L3MBTL1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11773074-B2 | Method for aerobic oxidative coupling of thiophenes with a ligand-supported palladium catalyst | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2023-10-03 | — | — | US | claimed |
| US-20210047285-A1 | Method for Aerobic Oxidative Coupling of Thiophenes with a Ligand-Supported Palladium Catalyst | WISCONSIN ALUMNI RESEARCH FOUNDATION | 2021-02-18 | — | — | US | claimed |
| US-10858334-B2 | Method for aerobic oxidative coupling of thiophenes with a ligand-supported palladium catalyst | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2020-12-08 | — | — | US | claimed |
| US-20190210993-A1 | Method for Aerobic Oxidative Coupling of Thiophenes with a Ligand-Supported Palladium Catalyst | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2019-07-11 | — | — | US | claimed |
| EP-2246376-B1 | Method for preparing particles with a conjugated polymer shell | LEIBNIZ INST POLYMERFORSCHUNG (DE) | 2014-03-05 | — | — | EP | claimed |
| EP-2246376-A1 | Method for preparing particles with a conjugated polymer shell | Leibniz-Institut für Polymerforschung Dresden e.V. (DE) | 2010-11-03 | — | — | EP | claimed |
| US-11833494-B2 | Catalysts and methods for forming alkenyl substituted arenes | UNIVERSITY OF VIRGINIA PATENT FOUNDATION (US) | 2023-12-05 | — | — | US | disclosed |
| US-11773074-B2 | Method for aerobic oxidative coupling of thiophenes with a ligand-supported palladium catalyst | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2023-10-03 | — | — | US | disclosed |
| US-11772083-B2 | Catalysts and methods for forming alkenyl and alkyl substituted arenes | UNIVERSITY OF VIRGINIA PATENT FOUNDATION (US) | 2023-10-03 | — | — | US | disclosed |
| US-20230173476-A1 | CATALYSTS AND METHODS FOR FORMING ALKENYL SUBSTITUTED ARENES | UNIVERSITY OF VIRGINIA PATENT FOUNDATION | 2023-06-08 | — | — | US | disclosed |
| US-20210283587-A1 | CATALYSTS AND METHODS FOR FORMING ALKENYL AND ALKYL SUBSTITUTED ARENES | UNIVERSITY OF VIRGINIA PATENT FOUNDATION | 2021-09-16 | — | — | US | disclosed |
| US-10967364-B2 | Catalysts and methods for forming alkenyl and alkyl substituted arenes | UNIVERSITY OF VIRGINIA PATENT FOUNDATION (US) | 2021-04-06 | — | — | US | disclosed |
| US-20210047285-A1 | Method for Aerobic Oxidative Coupling of Thiophenes with a Ligand-Supported Palladium Catalyst | WISCONSIN ALUMNI RESEARCH FOUNDATION | 2021-02-18 | — | — | US | disclosed |
| US-10858334-B2 | Method for aerobic oxidative coupling of thiophenes with a ligand-supported palladium catalyst | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2020-12-08 | — | — | US | disclosed |
| US-20190210993-A1 | Method for Aerobic Oxidative Coupling of Thiophenes with a Ligand-Supported Palladium Catalyst | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2019-07-11 | — | — | US | disclosed |
| US-20180065116-A1 | CATALYSTS AND METHODS FOR FORMING ALKENYL AND ALKYL SUBSTITUTED ARENES | UNIVERSITY OF VIRGINIA | 2018-03-08 | — | — | US | disclosed |
| WO-2016154416-A1 | CATALYSTS AND METHODS FOR FORMING ALKENYL AND ALKYL SUBSTITUTED ARENES | UNIVERSITY OF VIRGINIA PATENT FOUNDATION (US) | 2016-09-29 | — | — | WO | disclosed |
| EP-2246376-B1 | Method for preparing particles with a conjugated polymer shell | LEIBNIZ INST POLYMERFORSCHUNG (DE) | 2014-03-05 | — | — | EP | disclosed |
| EP-2246376-A1 | Method for preparing particles with a conjugated polymer shell | Leibniz-Institut für Polymerforschung Dresden e.V. (DE) | 2010-11-03 | — | — | EP | disclosed |
| EP-2246376-A1 | Method for preparing particles with a conjugated polymer shell | Leibniz-Institut für Polymerforschung Dresden e.V. (DE) | 2010-11-03 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10858334-B2 | Method for aerobic oxidative coupling of thiophenes with a ligand-supported palladium catalyst | PPOX, TST, COX6C | TDP1 1835/4885CYP1B1 517/4885ALDH1A1 613/4885 |
| US-11773074-B2 | Method for aerobic oxidative coupling of thiophenes with a ligand-supported palladium catalyst | PPOX, TST, COX6C | TDP1 1835/4885CYP1B1 517/4885ALDH1A1 613/4885 |
| US-20190210993-A1 | Method for Aerobic Oxidative Coupling of Thiophenes with a Ligand-Supported Palladium Catalyst | PPOX, TST, COX6C | TDP1 1835/4885CYP1B1 517/4885ALDH1A1 613/4885 |
| US-10967364-B2 | Catalysts and methods for forming alkenyl and alkyl substituted arenes | ALKBH3, SOD1, GARS1 | TDP1 1175/4885CYP1B1 1971/4885ALDH1A1 682/4885 |
| US-20210283587-A1 | CATALYSTS AND METHODS FOR FORMING ALKENYL AND ALKYL SUBSTITUTED ARENES | ALKBH3, SOD1, GARS1 | TDP1 1175/4885CYP1B1 1971/4885ALDH1A1 682/4885 |
| US-11833494-B2 | Catalysts and methods for forming alkenyl substituted arenes | SOD1, ALKBH3, HACL2 | TDP1 1205/4885CYP1B1 2145/4885ALDH1A1 818/4885 |
| US-11772083-B2 | Catalysts and methods for forming alkenyl and alkyl substituted arenes | ALKBH3, SOD1, GARS1 | TDP1 1175/4885CYP1B1 1971/4885ALDH1A1 682/4885 |
| US-20230173476-A1 | CATALYSTS AND METHODS FOR FORMING ALKENYL SUBSTITUTED ARENES | SOD1, ALKBH3, HACL2 | TDP1 1205/4885CYP1B1 2145/4885ALDH1A1 818/4885 |
| US-20180065116-A1 | CATALYSTS AND METHODS FOR FORMING ALKENYL AND ALKYL SUBSTITUTED ARENES | ALKBH3, SOD1, GARS1 | TDP1 1175/4885CYP1B1 1971/4885ALDH1A1 682/4885 |
| US-20210047285-A1 | Method for Aerobic Oxidative Coupling of Thiophenes with a Ligand-Supported Palladium Catalyst | PPOX, TST, COX6C | TDP1 1835/4885CYP1B1 517/4885ALDH1A1 613/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.