SCHEMBL10233139

SCHEMBL10233139

COCCCNc1nc(N(C)c2c(C)cc(C)cc2C)nc(NCCCOC)c1N=Nc1nn(-c2nc3ccccc3s2)cc1C#N

nearest known ligand 0.38

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
▸ KDM4E B2RXH2 5/20 0.38
▸ MAPT P10636 3/20 0.38
▸ ALDH1A1 P00352 3/20 0.37
▸ PKM P14618 2/20 0.37
▸ CFTR P13569 10/20 0.34
▸ NPC1 O15118 1/20 0.34
▸ RAB9A P51151 1/20 0.34
▸ SMN1; SMN2 Q16637 1/20 0.34
▸ L3MBTL1 Q9Y468 1/20 0.32
▸ KMT2A Q03164 2/20 0.32
▸ CYP1A2 P05177 1/20 0.32
▸ CYP3A4 P08684 1/20 0.32
▸ CYP2C9 P11712 1/20 0.32
▸ HPGD P15428 1/20 0.32
▸ CYP2C19 P33261 1/20 0.32
▸ TDP1 Q9NUW8 1/20 0.32
▸ CA12 O43570 1/20 0.32
▸ CA2 P00918 1/20 0.32
▸ CA9 Q16790 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13310916 0.91 KDM4E (0.37) KDM4EMAPTALDH1A1PKMCFTR
SCHEMBL10233130 0.88 KDM4E (0.39) KDM4EMAPTALDH1A1PKMCFTR
SCHEMBL13311000 0.87 KDM4E (0.38) KDM4EMAPTALDH1A1PKMCFTR
SCHEMBL10233204 0.86 MAPT (0.38) KDM4EMAPTALDH1A1PKMCFTR
SCHEMBL13310913 0.85 SMN1; SMN2 (0.36) KDM4EMAPTALDH1A1PKMCFTR
SCHEMBL14452314 0.83 MAPT (0.35) KDM4EMAPTALDH1A1PKMCFTR
SCHEMBL13310999 0.83 MAPT (0.35) KDM4EMAPTALDH1A1PKMCFTR
SCHEMBL10233105 0.83 MAPT (0.33) MAPTNPC1RAB9A
SCHEMBL10233109 0.81 MAPT (0.35) KDM4EMAPTALDH1A1PKMNPC1
SCHEMBL10233110 0.80 MAPT (0.32) MAPTNPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8293436-B2 Oxime derivative, photopolymerizable composition, color filter, and process for producing the same FUJIFILM CORPORATION (JP) 2012-10-23 — — US disclosed
US-8293436-B2 Oxime derivative, photopolymerizable composition, color filter, and process for producing the same FUJIFILM CORPORATION (JP) 2012-10-23 — — US disclosed
US-20120037860-A1 DYE-CONTAINING NEGATIVE CURABLE COMPOSITION, COLOR FILTER AND METHOD FOR PRODUCING THE SAME FUJIFILM CORPORATION (JP) 2012-02-16 — — US disclosed
US-20120037860-A1 DYE-CONTAINING NEGATIVE CURABLE COMPOSITION, COLOR FILTER AND METHOD FOR PRODUCING THE SAME FUJIFILM CORPORATION (JP) 2012-02-16 — — US disclosed
US-8057969-B2 Dye-containing negative curable composition, color filter and method for producing the same FUJIFILM CORPORATION (JP) 2011-11-15 — — US disclosed
US-8057969-B2 Dye-containing negative curable composition, color filter and method for producing the same FUJIFILM CORPORATION (JP) 2011-11-15 — — US disclosed
US-7740995-B2 Azo compound, colored curable composition, color filter and manufacturing method therefor FUJIFILM CORPORATION (JP) 2010-06-22 — — US disclosed
US-7740995-B2 Azo compound, colored curable composition, color filter and manufacturing method therefor FUJIFILM CORPORATION (JP) 2010-06-22 — — US disclosed
US-20100104976-A1 OXIME DERIVATIVE, PHOTOPOLYMERIZABLE COMPOSITION, COLOR FILTER, AND PROCESS FOR PRODUCING THE SAME FUJIFILM CORPORATION (JP) 2010-04-29 — — US disclosed
US-20100104976-A1 OXIME DERIVATIVE, PHOTOPOLYMERIZABLE COMPOSITION, COLOR FILTER, AND PROCESS FOR PRODUCING THE SAME FUJIFILM CORPORATION (JP) 2010-04-29 — — US disclosed
US-7674503-B2 Oxime derivative, photopolymerizable composition, color filter, and process for producing the same FUJIFILM CORPORATION (JP) 2010-03-09 — — US disclosed
US-7674503-B2 Oxime derivative, photopolymerizable composition, color filter, and process for producing the same FUJIFILM CORPORATION (JP) 2010-03-09 — — US disclosed
US-20070254240-A1 Dye-containing negative curable composition, color filter and method for producing the same FUJIFILM CORPORATION (JP) 2007-11-01 — — US disclosed
US-20070254240-A1 Dye-containing negative curable composition, color filter and method for producing the same FUJIFILM CORPORATION (JP) 2007-11-01 — — US disclosed
US-20070203255-A1 Oxime derivative, photopolymerizable composition, color filter, and process for producing the same FUJIFILM CORPORATION (JP) 2007-08-30 — — US disclosed
US-20070203255-A1 Oxime derivative, photopolymerizable composition, color filter, and process for producing the same FUJIFILM CORPORATION (JP) 2007-08-30 — — US disclosed
US-20070037076-A1 Pyrimidine azo dye, curable tri- or higher-functional (meth)acrylic ester monomers, alkali-soluble (meth)acrylic resin binder, photoinitiators ( traizines, benzophenones, lophine dimer etc.); curing, developing; for forming a color filter for use in a liquid crystal display FUJI PHOTO FILM CO., LTD. 2007-02-15 — — US disclosed
US-20070037076-A1 Pyrimidine azo dye, curable tri- or higher-functional (meth)acrylic ester monomers, alkali-soluble (meth)acrylic resin binder, photoinitiators ( traizines, benzophenones, lophine dimer etc.); curing, developing; for forming a color filter for use in a liquid crystal display FUJI PHOTO FILM CO., LTD. 2007-02-15 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100104976-A1 OXIME DERIVATIVE, PHOTOPOLYMERIZABLE COMPOSITION, COLOR FILTER, AND PROCESS FOR PRODUCING THE SAME PPOX, CYBA, HBB KDM4E 228/4885MAPT 2701/4885ALDH1A1 617/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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