SCHEMBL10233152

SCHEMBL10233152

COCC(C)Nc1nc(Nc2c(C)cc(C)cc2C)nc(NCCC(=O)O)c1N=Nc1nn(-c2ncccn2)cc1C#N

nearest known ligand 0.33

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
▸ KDM4E B2RXH2 1/20 0.33
▸ USP2 O75604 1/20 0.33
▸ ALDH1A1 P00352 1/20 0.33
▸ GAA P10253 1/20 0.33
▸ HPGD P15428 1/20 0.33
▸ CASP1 P29466 1/20 0.33
▸ CASP7 P55210 1/20 0.33
▸ HSD17B10 Q99714 1/20 0.33
▸ CFTR P13569 4/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10233517 0.92 KDM4E (0.31) KDM4EUSP2ALDH1A1GAAHPGD
SCHEMBL12124873 0.91 — —
SCHEMBL10278607 0.91 — —
SCHEMBL10233154 0.82 KDM4E (0.31) KDM4EUSP2HSD17B10CFTR
SCHEMBL13310898 0.80 JAK2 (0.33) KDM4EALDH1A1
SCHEMBL10278254 0.80 — —
SCHEMBL10233142 0.80 CFTR (0.34) CFTR
SCHEMBL12124890 0.79 — —
SCHEMBL10233132 0.78 — —
SCHEMBL10278731 0.78 — —

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8293436-B2 Oxime derivative, photopolymerizable composition, color filter, and process for producing the same FUJIFILM CORPORATION (JP) 2012-10-23 — — US disclosed
US-20120037860-A1 DYE-CONTAINING NEGATIVE CURABLE COMPOSITION, COLOR FILTER AND METHOD FOR PRODUCING THE SAME FUJIFILM CORPORATION (JP) 2012-02-16 — — US disclosed
US-20120037860-A1 DYE-CONTAINING NEGATIVE CURABLE COMPOSITION, COLOR FILTER AND METHOD FOR PRODUCING THE SAME FUJIFILM CORPORATION (JP) 2012-02-16 — — US disclosed
US-8057969-B2 Dye-containing negative curable composition, color filter and method for producing the same FUJIFILM CORPORATION (JP) 2011-11-15 — — US disclosed
US-8057969-B2 Dye-containing negative curable composition, color filter and method for producing the same FUJIFILM CORPORATION (JP) 2011-11-15 — — US disclosed
US-7740995-B2 Azo compound, colored curable composition, color filter and manufacturing method therefor FUJIFILM CORPORATION (JP) 2010-06-22 — — US disclosed
US-20100104976-A1 OXIME DERIVATIVE, PHOTOPOLYMERIZABLE COMPOSITION, COLOR FILTER, AND PROCESS FOR PRODUCING THE SAME FUJIFILM CORPORATION (JP) 2010-04-29 — — US disclosed
US-20100104976-A1 OXIME DERIVATIVE, PHOTOPOLYMERIZABLE COMPOSITION, COLOR FILTER, AND PROCESS FOR PRODUCING THE SAME FUJIFILM CORPORATION (JP) 2010-04-29 — — US disclosed
US-7674503-B2 Oxime derivative, photopolymerizable composition, color filter, and process for producing the same FUJIFILM CORPORATION (JP) 2010-03-09 — — US disclosed
US-7674503-B2 Oxime derivative, photopolymerizable composition, color filter, and process for producing the same FUJIFILM CORPORATION (JP) 2010-03-09 — — US disclosed
US-20070254240-A1 Dye-containing negative curable composition, color filter and method for producing the same FUJIFILM CORPORATION (JP) 2007-11-01 — — US disclosed
US-20070254240-A1 Dye-containing negative curable composition, color filter and method for producing the same FUJIFILM CORPORATION (JP) 2007-11-01 — — US disclosed
US-20070203255-A1 Oxime derivative, photopolymerizable composition, color filter, and process for producing the same FUJIFILM CORPORATION (JP) 2007-08-30 — — US disclosed
US-20070203255-A1 Oxime derivative, photopolymerizable composition, color filter, and process for producing the same FUJIFILM CORPORATION (JP) 2007-08-30 — — US disclosed
US-20070037076-A1 Pyrimidine azo dye, curable tri- or higher-functional (meth)acrylic ester monomers, alkali-soluble (meth)acrylic resin binder, photoinitiators ( traizines, benzophenones, lophine dimer etc.); curing, developing; for forming a color filter for use in a liquid crystal display FUJI PHOTO FILM CO., LTD. 2007-02-15 — — US disclosed
US-20070037076-A1 Pyrimidine azo dye, curable tri- or higher-functional (meth)acrylic ester monomers, alkali-soluble (meth)acrylic resin binder, photoinitiators ( traizines, benzophenones, lophine dimer etc.); curing, developing; for forming a color filter for use in a liquid crystal display FUJI PHOTO FILM CO., LTD. 2007-02-15 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100104976-A1 OXIME DERIVATIVE, PHOTOPOLYMERIZABLE COMPOSITION, COLOR FILTER, AND PROCESS FOR PRODUCING THE SAME PPOX, CYBA, HBB KDM4E 228/4885USP2 2520/4885ALDH1A1 617/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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