SCHEMBL1023482

SCHEMBL1023482

C=C(C(F)(F)C(F)(F)C(F)(F)C(F)(F)F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F

nearest known ligand 0.46

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.46
LMNA P02545 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4426053 0.97 THRB (0.50) THRBLMNA
SCHEMBL1021902 0.97 THRB (0.50) THRBLMNA
SCHEMBL1221730 0.81 THRB (0.42) THRBLMNA
SCHEMBL22011346 0.78 THRB (0.32) THRB
SCHEMBL1275959 0.78 THRB (0.43) THRBLMNA
SCHEMBL9717162 0.75 THRB (0.42) THRBLMNA
SCHEMBL1221763 0.75 THRB (0.42) THRBLMNA
SCHEMBL29616992 0.75 THRB (0.48) THRBLMNA
SCHEMBL31470114 0.75 THRB (0.48) THRBLMNA
SCHEMBL31470129 0.75 THRB (0.48) THRBLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 243 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3664770-B1 THERAPEUTIC GAS INFUSED COSMETIC AND METHODS OF INFUSION TETROUS INC (US) 2024-12-04 EP claimed
WO-2024097997-A2 PHOTOACOUSTIC VAPORIZATION OF EXOSKELETAL AND ENDOSKELETAL DROPLETS THE REGENTS OF THE UNIVERSITY OF COLORADO (US) 2024-05-10 WO claimed
US-10758483-B2 Fluoropolymer emulsions with perhalogenated stabilizer for the delivery of hydrophobic drugs WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2020-09-01 US claimed
US-20200101014-A1 Stable Theranostic and Therapeutic Nanoemulsions Using Triphilic Semifluorinated Amphiphiles WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2020-04-02 US claimed
US-10426727-B2 Fluoropolymer emulsions with branched semifluorinated block copolymer or phospholipid surfactant for the delivery of hydrophobic drugs WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2019-10-01 US claimed
WO-2018187236-A1 STABLE THERANOSTIC AND THERAPEUTIC NANOEMULSIONS USING TRIPHILIC SEMIFLUORINATED AMPHIPHILES WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2018-10-11 WO claimed
US-20170100336-A1 Fluoropolymer Emulsions with Perhalogenated Stabilizer for the Delivery of Hydrophobic Drugs WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2017-04-13 US claimed
US-20170049699-A1 Fluoropolymer Emulsions with Branched Semifluorinated Block Copolymer or Phospholipid Surfactant for the Delivery of Hydrophobic Drugs WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2017-02-23 US claimed
EP-2099408-B1 FLUOROPOLYMER-BASED EMULSIONS FOR THE INTRAVENOUS DELIVERY OF FLUORINATED VOLATILE ANESTHETICS WISCONSIN ALUMNI RES FOUND (US) 2016-10-05 EP claimed
WO-2015164756-A1 FLUOROPOLYMER EMULSIONS WITH PERHALOGENATED STABILIZER FOR THE DELIVERY OF HYDROPHOBIC DRUGS WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2015-10-29 WO claimed
WO-2000040252-A1 NOVEL POLYMER FORMULATIONS CONTAINING PERFLUORINATED COMPOUNDS FOR THE ENGINEERING OF CELLS AND TISSUES FOR TRANSPLANTATION THAT IMPROVES CELL METABOLISM AND SURVIVAL, AND METHODS FOR MAKING SAME BIOMM, INCORPORATED (US) 2000-07-13 WO claimed
US-5989918-A DETERMINING ABSORPTION, DISTRIBUTION, METABOLISM, EXCRETION AND PHARMACOKINETICS OF TEST COMPOUND IN ISOLATED LIVE ORGAN USING FLUOROCARBON EMULSION AS BLOOD SUBSTITUTE, ADDING COMPOUND, DISRUPTING EMULSION OF SAMPLE, ANALYSIS CHIRON CORPORATION (US) 1999-11-23 US claimed
EP-0923733-A1 METHOD FOR ANALYSING ABSORPTION, DISTRIBUTION, METABOLISM, EXCRETION (ADME) AND PHARMACOKINETICS PROPERTIES OF COMPOUND MIXTURES CHIRON CORPORATION (US) 1999-06-23 EP claimed
WO-1998009166-A1 METHOD FOR ANALYSING ABSORPTION, DISTRIBUTION, METABOLISM, EXCRETION (ADME) AND PHARMACOKINETICS PROPERTIES OF COMPOUND MIXTURES CHIRON CORPORATION (US) 1998-03-05 WO claimed
EP-0515676-B1 SYSTEM FOR OXYGENATION OF THE HEART USING SUBPERICARDIAL FLUIDS MALLINCKRODT MEDICAL INC (US) 1997-03-12 EP claimed
US-5595687-A INJECTABLE FLUOROCARBON EMULSION USEFUL IN CORONARY ANGIOPLASTY, CANCER THERAPY THOMAS JEFFERSON UNIVERSITY (US) 1997-01-21 US claimed
EP-0666736-B1 STABILIZATION OF FLUOROCARBON EMULSIONS ALLIANCE PHARMA (US) 1996-12-18 EP claimed
US-5085630-A Treatment of hypoxic-ischemic neurologic tissue THOMAS JEFFERSON UNIVERSITY (US) 1992-02-04 US claimed
US-4981691-A AMINO ACIDS THOMAS JEFFERSON UNIVERSITY (US) 1991-01-01 US claimed
EP-0118281-B1 IMPROVEMENTS IN AND RELATING TO A METHOD OF DETECTING A CERTAIN GAS IN AN ANIMAL CHILDREN'S HOSPITAL MEDICAL CENTER (US) 1990-10-03 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10426727-B2 Fluoropolymer emulsions with branched semifluorinated block copolymer or phospholipid surfactant for the delivery of hydrophobic drugs FFAR3, FFAR1, FAU THRB 1404/4885LMNA 2221/4885
US-20170049699-A1 Fluoropolymer Emulsions with Branched Semifluorinated Block Copolymer or Phospholipid Surfactant for the Delivery of Hydrophobic Drugs FFAR3, FFAR1, FAU THRB 1404/4885LMNA 2221/4885
US-10758483-B2 Fluoropolymer emulsions with perhalogenated stabilizer for the delivery of hydrophobic drugs PFN1, FFAR1, FAU THRB 2284/4885LMNA 2034/4885
US-20170100336-A1 Fluoropolymer Emulsions with Perhalogenated Stabilizer for the Delivery of Hydrophobic Drugs PFN1, FFAR1, FAU THRB 2284/4885LMNA 2034/4885
US-20200101014-A1 Stable Theranostic and Therapeutic Nanoemulsions Using Triphilic Semifluorinated Amphiphiles EWSR1, TPT1, FOLR1 THRB 2649/4885LMNA 3320/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.