SCHEMBL1023508

SCHEMBL1023508

CCN(CC)CCOc1ccc(Cl)c(Cl)c1

nearest known ligand 0.84

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.84
MAPT P10636 2/20 0.58
KMT2A Q03164 2/20 0.58
CHRNA7 P36544 1/20 0.58
KCNH2 Q12809 1/20 0.57
SIGMAR1 Q99720 3/20 0.53
EBP Q15125 1/20 0.53
TSHR P16473 1/20 0.53
HTT P42858 2/20 0.52
POLB P06746 1/20 0.52
SMARCA2 P51531 1/20 0.52
SMN1; SMN2 Q16637 1/20 0.52
NPSR1 Q6W5P4 1/20 0.52
MAOB P27338 1/20 0.52
CYP1A2 P05177 1/20 0.51
LTA4H P09960 1/20 0.51
CYP2D6 P10635 1/20 0.51
CYP2C9 P11712 1/20 0.51
CYP2C19 P33261 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29413774 1.00 KDM4E (0.84) KDM4EMAPTKMT2ACHRNA7KCNH2
SCHEMBL10358381 0.87 KDM4E (0.65) KDM4EMAPTKMT2ACHRNA7SIGMAR1
SCHEMBL3863505 0.85 KDM4E (0.63) KDM4EMAPTKMT2ACHRNA7SIGMAR1
SCHEMBL14453655 0.85 KDM4E (0.63) KDM4EMAPTKMT2ACHRNA7SIGMAR1
SCHEMBL10409449 0.85 KCNH2 (0.68) KDM4EKMT2AKCNH2SMN1; SMN2
Hydrochloric Acid SCHEMBL10409505 0.83 KCNH2 (0.67) KDM4EKMT2AKCNH2SMN1; SMN2
SCHEMBL11254086 0.82 KDM4E (0.58) KDM4EMAPTKMT2ACHRNA7SIGMAR1
SCHEMBL4592183 0.82 KDM4E (0.58) KDM4EMAPTKMT2ACHRNA7SIGMAR1
SCHEMBL9706125 0.81 EBP (0.72) MAPTKMT2ACHRNA7KCNH2SIGMAR1
SCHEMBL10358944 0.80 EBP (0.62) KDM4EMAPTKMT2ACHRNA7KCNH2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 168 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114213468-B Iridium complex and application thereof in yield-increasing amine synthesis 河南省科学院高新技术研究中心 2023-11-03 CN claimed
CN-115651666-A Reseeding seed dressing agent for ecological restoration of desert grasslands and preparation method and application thereof 宁夏回族自治区草原工作站 2023-01-31 CN claimed
CN-115281190-A Biological agent for promoting photosynthesis of wheat and preparation method thereof 山东省农业科学院作物研究所 2022-11-04 CN claimed
CN-114982757-A Method for preparing ester or tertiary amine plant growth regulator aqueous solution 郑州尼采生物科技有限公司 2022-09-02 CN claimed
CN-111790739-B Method for repairing cadmium-polluted soil by using crassula argentea 河南省科学院高新技术研究中心 2022-04-19 CN claimed
CN-114213468-A Metal iridium complex and application thereof in amine synthesis for increasing yield 河南省科学院高新技术研究中心 2022-03-22 CN claimed
CN-112159274-A Microbial granular inoculant with biocontrol nutrition function 山东土木启生物科技有限公司 2021-01-01 CN claimed
CN-111790739-A Method for repairing cadmium-polluted soil by using crassula argentea 河南省科学院高新技术研究中心 2020-10-20 CN claimed
CN-109644875-A A kind of method of celery microspore callus differentiation and regeneration plant 江苏润知农业技术服务有限公司 2019-04-19 CN claimed
CN-109369284-A A kind of rice Water-soluble fertilizer special and preparation method thereof 江苏心实肥业集团有限公司 2019-02-22 CN claimed
CN-103125520-A Conditioning agent for low temperature resistance corn strong stalk production increasing and quality improving and preparation method and application thereof UNIV NORTHEAST AGRICULTURAL 2013-06-05 CN claimed
CN-101856020-A Weeding safety additive KERAN SHEN 2010-10-13 CN claimed
US-7264951-B1 Enhanced production of taxol and taxanes by cell cultures of Taxus species PHYTON, INC. (US) 2007-09-04 US claimed
US-20070026506-A1 METHOD FOR THE PRODUCTION OF TAXOL AND/OR TAXANES FROM CULTURES OF HAZEL CELLS CENTRO BIOTECNOLOGIE AVANZATE (IT) 2007-02-01 US claimed
EP-1739184-A1 Method for the production of taxol and/or taxanes from cultures of hazel cells Centro Biotecnologie Avanzate (IT) 2007-01-03 EP claimed
EP-0109563-B1 METHOD OF INCREASING BIOMASS IN PLANTS US AGRICULTURE (US) 1990-10-10 EP claimed
US-4797153-A PLANT GROWTH REGULATORS THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (US) 1989-01-10 US claimed
EP-0109563-A2 Method of increasing biomass in plants THE UNITED STATES OF AMERICA as represented by the Secretary United States Department of Commerce (US) 1984-05-30 EP claimed
WO-1984001489-A1 METHOD OF INCREASING BIOMASS IN PLANTS US AGRICULTURE (US) 1984-04-26 WO claimed
US-4363188-A AMINE PLANT GROWTH REGULATORS LOVELACE ALAN M ADMINISTRATOR 1982-12-14 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070026506-A1 METHOD FOR THE PRODUCTION OF TAXOL AND/OR TAXANES FROM CULTURES OF HAZEL CELLS TUBB3, TUBB1, COLGALT1 KDM4E 4456/4885MAPT 383/4885KMT2A 1598/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.