Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD3 | P35462 | 10/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 10/20 | 0.42 |
| ▸ | DRD2 | P14416 | 9/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12313185 | 0.86 | KCNH2 (0.52) | DRD3KCNH2DRD2 | |
| SCHEMBL3769913 | 0.86 | KCNH2 (0.52) | DRD3KCNH2DRD2 | |
| SCHEMBL3769912 | 0.86 | KCNH2 (0.52) | DRD3KCNH2DRD2 | |
| SCHEMBL11911756 | 0.86 | KCNH2 (0.52) | DRD3KCNH2DRD2 | |
| SCHEMBL3397256 | 0.86 | KCNH2 (0.52) | DRD3KCNH2DRD2 | |
| SCHEMBL11915231 | 0.86 | KCNH2 (0.52) | DRD3KCNH2DRD2 | |
| SCHEMBL378256 | 0.83 | DRD3 (0.55) | DRD3KCNH2DRD2 | |
| SCHEMBL13089084 | 0.83 | DRD3 (0.55) | DRD3KCNH2DRD2 | |
| SCHEMBL13312906 | 0.83 | DRD2 (0.53) | DRD3KCNH2DRD2 | |
| SCHEMBL12313199 | 0.76 | DRD3 (0.45) | DRD3KCNH2DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2060570-B1 | Azabicyclo[3.1.0] hexane derivatives useful as modulators of dopamine D3 receptors | GLAXO GROUP LTD (GB) | 2012-01-25 | — | — | EP | disclosed |
| EP-2060570-A2 | Azabicyclo(3.1.0) hexane derivatives useful as modulators of dopamine D3 receptors | Glaxo Group Limited (GB) | 2009-05-20 | — | — | EP | disclosed |